Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
1224 6 |
Ultima descărcare din IBN: 2022-04-30 16:51 |
Căutarea după subiecte similare conform CZU |
543.9+547 (1) |
Анализ посредством биологических и биохимических реакций. Биологические методы, применяемые для аналитических целей (9) |
Органическая химия (475) |
SM ISO690:2012 SUCMAN, Natalia, POGREBNOI, Vsevolod, OBUSHAK, Mykola, MELNIK, E., KRAVTSOV, Victor, MAKAEV, Fliur. The synthesis of new spirolactones from substituted isatins . In: Chemistry Journal of Moldova, 2015, nr. 1(10), pp. 64-70. ISSN 1857-1727. DOI: https://doi.org/10.19261/cjm.2015.10(1).09 |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Chemistry Journal of Moldova | |
Numărul 1(10) / 2015 / ISSN 1857-1727 /ISSNe 2345-1688 | |
|
|
DOI: https://doi.org/10.19261/cjm.2015.10(1).09 | |
CZU: 543.9+547 | |
Pag. 64-70 | |
Descarcă PDF | |
Rezumat | |
Interaction of N-ethyl isatin 3 with dimethyl acetylenedicarboxylate in the presence triphenylphosphine has led to good selectivity of methyl 1’-ethyl-4-methoxy-2’,5-dioxo-5H-spiro[furan-2,3’-indoline]-3-carboxylate 4 formation. Similar yields of spirolactones 6,8 were obtained by addition of dimethyl acetylenedicarboxylate to 5-bromo functionalized isatins 5,7. However, reaction of N-butyl isatin 9 resulted in formation of an inseparable mixture of compounds. Treatment of N-benzyl isatin 10 and dimethyl acetylenedicarboxylate with triphenylphosphine proceeded with reduced selectivity of the spirooxindole 11 formation. |
|
Cuvinte-cheie spirolactones, isatins, dimethyl acetylenedicarboxylate., triphenylphosphine |
|
|