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Ultima descărcare din IBN: 2023-12-15 11:58 |
SM ISO690:2012 GROSU, Aurel. Markerii disfuncţiei endoteliale şi inflamaţiei
în tromboza venoasă profundă idiopatică. In: Curierul Medical, 2013, nr. 1(56), pp. 20-25. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 1(56) / 2013 / ISSN 1875-0666 | ||||||
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Pag. 20-25 | ||||||
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Idiopathic deep vein thrombosis is a process of venous thrombosis with the absence of challenging factors (thrombophilia, cancer, immobilization, trauma, surgical intervention etc.). In the present study, the admission values of the endothelium dysfunction and inflammation markers have been assayed in 78 patients with idiopathic deep vein thrombosis. The nitric oxide circulating level was reduced by 56.3% that correlated with a flow mediated
brachial artery dilation decrease by 47% and with a carotid artery intima-media thickness rise by 77.6%. Likewise, an evident activation of inflammatory response has been attested that was manifested by an increase in serum levels of C reactive protein and IL-6 by 3.14 and 4.7 times. Thus, the shifting markers indicate a pathogenic role of endothelium dysfunction and inflammation in idiopathic deep vein thrombosis evolution, yet, on the other hand, they can be used as diagnostic and prognostic predictors of the malady. |
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Cuvinte-cheie idiopathic venous thrombosis, endothelial and inflammation markers. |
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