Cardiovascular syndromes with primary immunodeficiency
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2023-06-11 19:09
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616.1:612.017.1:575.1-053.2 (1)
Патология сердечно-сосудистой системы. Сердечно-сосудистые заболевания (1114)
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Общая генетика. Общая цитогенетика. Иммуногенетика. Эволюционное учение. Видообразование. Филогенез (497)
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RODOMAN, Iulia, PÎRŢU, Lucia, SACARĂ, Victoria, ŞCIUCA, Svetlana, PALII, Ina. Manifestări cardiovasculare în imunodeficiențele primare. In: Imunopedia, Ed. Ediția a 2-a, 9-10 septembrie 2022, Chişinău. Chişinău: Centrul Editorial-Poligrafic Medicina, 2022, Ediția a 2-a, pp. 81-95. ISBN 978-9975-82-300-5.
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Imunopedia
Ediția a 2-a, 2022
Conferința "Imunopedia"
Ediția a 2-a, Chişinău, Moldova, 9-10 septembrie 2022

Cardiovascular syndromes with primary immunodeficiency

Manifestări cardiovasculare în imunodeficiențele primare

CZU: 616.1:612.017.1:575.1-053.2

Pag. 81-95

Rodoman Iulia12, Pîrţu Lucia21, Sacară Victoria2, Şciuca Svetlana21, Palii Ina12
 
1 Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“,
2 IMSP Institutul Mamei şi Copiluluii
 
 
 
Disponibil în IBN: 30 ianuarie 2023


Rezumat

The medical community generally identified a rising amount of patients with primary immune deficiency (PID) and cardiovascular system (CVS) comorbidities last year. These CVS malformations might be explained by infectious or autoimmune etiologies, genetic aspects, and the immune system participating in the CVS tissue development. Here, we describe combinations of immune and CVS defects from comprehensive literature. In addition to some famous combinations of PID with CVS abnormalities, such as DiGeorge syndrome and CHARGE anomaly, here are described CHD in combination with Omenn syndrome, DNA repair defects, common variable immunodeficiency, Roifman syndrome, and others. Moreover, we describe the vascular anomalies in chronic mucocutaneous candidiasis, chronic granulomatous disease, and Wiskott–Aldrich syndrome. In conclusion, the expanding range of PID needs advanced attention to the potential CVS involvement as an essential benefactor in diagnosing and managing the disease.