Climate change affects the viability, growth capacity and behavior of many fungi. For example, the authors G. Gilardi, A. Garibaldi, M. Gullino (2018) found in Italian conditions that the increase in temperature and concentration of CO2 in the air has contributed to the spread of hosts and pathogenicity of the fungus Fusarium equiseti which is usually considered a species with low pathogenicity. In connection with the increasingly severe climatic disturbances that most directly affect the soil biotic systems, the aim of the present research was to elucidate the influence of the temperature factor on the growth of some of the most widespread fungi in the conditions of the Republic of Moldova on common wheat – F avenaceum, F. equseti and F. oxysporum – causative agents of root rot. Research on the growth of fungal colonies under controlled conditions on nutrient medium PDA (Potato Dextrose Agar) at temperatures of 24°C (optimal), 10°C, 35°C – limiting, showed that the thermal factor had the highest share in the source of variation of the radial growth of the fungi (81.83 - 87.33%). The fungal species factor accounted for 2.35-5.80%, and the isolate factor – 0.16-0.27%. It should be noted that the temperature x fungus interactions recorded quite significant values – 9.51-11.40%, which indicates that in the formation of fungal complexes that initiate and produce wheat disease, an important role is played by the temperature level in the soil.