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SM ISO690:2012 HAREA, Patricia, MISHINA, Anna, HAREA, Adrian, DOBREVA, Cristina, FUIOR-BULHAC, Liliana, PETROVICH, Virgil. Diagnosis and surgical treatment of ovarian tumors in pediatric patients. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 421. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Background. Ovarian tumors (OT) in children and adolescents is a fairly rare pathology. Objective of the study. To study the morphological structure, the particularities of the diagnosis and surgical treatment of OT in children and adolescents. Material and Methods. The database (n = 132) of OT in children and adolescents, operated in the surgical gynecology department at The Institute of Mother and Child in the period 2000-2019. Such imaging methods as USG, CT or MRI were used for the diagnosis and stratification of OT. Selectively, tumor markers were determined (CA-125, CEA, CA 19.9, αFP and β-hCG). Results. The mean age of patients with OT was 16.1 ± 0.2 years (95% CI: 15.64-16.41), including in 5 (3.8%) cases the patients were in the premenarche status. According to the radiological methods, the maximum size of OT were 9.9 ± 0.4 cm (from 3.8 to 32.1), and the minimum –7.9 ± 0.3 cm (from 2.6 to 26.5) and the volume - 624.8 ± 106.3 cm3. Depending on the size of OT, reference was made to large size (> 8 cm after Amies Oelschlager AM. Et al., 2016) in 64 (48.5%) cases and gigantic (> 15 cm after Ye LY. Et al., 2012) ) - 14 (10.6%) cases. The “morphological” USG index was 5.5 ± 0.2 (from 2 to 10), and the score ≥5 was in 98 (74.2%) cases. Unilateral OT were registered more often than bilateral ones (95.5% compared to 4.5%). Surgical treatment was performed by laparotomy (n = 100, 75.8%) and laparoscopy (n = 32, 24.2%). According to the volume of operations, tumorectomies with preservation of ovarian tissue - 105 (76.1%), annexectomies - 23 (16.7%), ovarectomies - 9 (6.5%) and partial resection of the ovaries - 1 (0.7%). Tumorectomies were performed more frequently using the laparoscopic method compared to laparotomies - 93.8% vs. -75% (p <0.05). At the histological examination it was established that in 130 (94.2%) cases TO were benign, malignant and borderline - 8 (5.8%). Among benign tumors, epithelial tumors (n = 72, 55.4%) and germinogenic tumors (n = 53, 40.8%) predominated. Recurrences in the late postoperative period were in 5 (4.7%) cases. Conclusions: In children and adolescents, benign OTs are more common. In more than half of the cases, OTs are large and giant. In most cases it is possible to perform tumorectomy with preservation of ovarian tissue |
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Cuvinte-cheie tumor, ovary, children, adolescents, tumoră, ovar, copii, adolescente |
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