The work presents the results of scientific research on the combinatorial performance between lines and families of Landrace breeds, according to reproduction indices and fattening qualities, as well as their own developmental performance (precocity, bacon layer thickness, body weight, viability, reproductive qualities (prolificacy, average number of piglets at weaning, batch and piglet weight at 60 days of age), appreciated the best variants of inter- and intrarasal combinations. New data were obtained on the reproductive and productive qualities of the lines used at ÎS "Moldsuinhibrid" in various interracial and intraracial combinations, appreciated the lines with the best combinatorial results, with the following performances: the prolificity of the Lin Sua and Danlaur line on average - 11, 1 piglet (252 combinations), the weight of a piglet at the age of 2 months of the line Lin Usa and Lin – 21,0 kg with the corresponding lot weight, 158 kg and 141 kg. The carried out studies allowed the identification of the most productive combinations, with the use of imported and locally selected boars of Landrace breeds in intrarasial and interracial crosses with locally selected sows. The work is a completion of previous studies on imported and locally selected pig breeds, which was the basis for the creation of selection nuclei for the efficiency of breeding of these breeds, through their differentiated use in the breeding program.