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Articolul urmator |
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SM ISO690:2012 CUŞNIR, Valeriu, DUMBRĂVEANU, Lilia, GROPPA, Liliana, CUŞNIR, Vitalie. Utilizarea preparatului bevacizumab în tratamentul complex al uveitelor non-infecțioase. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 473. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | |||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | |||||
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Background. Non-infectious uveitis is the inflammation of the uvea. This group of diseases with multiple etiology are a continuous challenge for ophthalmologists. Traditional treatment of uveitis could have a lot of adverse effects, that’s why the necessity of new medicines is still actual. Objective of the study. Evaluate the therapeutic efficacy of bevacizumab for non-infectious uveitis compared with traditional method of treatment and assessment of adverse reactions. Material and Methods. This study include 9 clinical cases with non-infectious uveitis, that were treated with bevacizumab and traditional methods of treatment according to latest protocols. Follow-up period was about 1-5 years. Often, bevacizumab was administrated repeatedly (2-3 times) to stabilise the remision for 1-5 years. Results. Inflammatory process was stabilized by administration of bevacizumab in anterior chamber. The effect prolong the remission with 4 months and improve central vision. It seems that the duration of remission is significant bigger compared to traditional method of treatment and repeated administration of drug have a cumulative effect. Conclusion. Traditional method of treatment of noninfectious uveitis with steroids make the management of disease more difficult, because of the multiple adverse reactions. Bevacizumab slow down the inflammatory process and prevent the complications of uveitis, like macular oedema and neovascular glaucoma. |
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Cuvinte-cheie uveitis, noninfectious uveitis, Bevacizumab, uveite, uveite non-infecțioase, bevacizumab |
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