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<identifier identifierType='DOI'>10.5281/zenodo.4028371</identifier>
<creators>
<creator>
<creatorName>Popa, A.N.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Negară, A.I.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Şoric, G.N.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Popescu, A.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='en'>Evolutionary particulars of COVID-19 in elderly patients</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2020</publicationYear>
<relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>2537-6373</relatedIdentifier>
<subjects>
<subject>COVID-19</subject>
<subject>elderly</subject>
<subject>mortality</subject>
<subject schemeURI='http://udcdata.info/' subjectScheme='UDC'>616.98:578.834.1]-053.9</subject>
</subjects>
<dates>
<date dateType='Issued'>2020-12-09</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Journal article</resourceType>
<descriptions>
<description xml:lang='en' descriptionType='Abstract'><p>Background: The new SARS-CoV-2 coronavirus affects a large number of people worldwide, and the elderly are particularly affected because of their vulnerability. Thus, the elderly patients and those with comorbidities have an increased risk of developing a severe disease and show an increased mortality rate. Although they may show mild symptoms of illness and low-grade fever in the early days, they may worsen clinically rapidly, requiring ongoing monitoring. Material and methods: The prospective study was performed on a group of 96 patients (mean age 61.41 &plusmn; 3.42 years), with a predominance of men, hospitalized in the Holy Trinity Hospital of Chisinau who met the clinical case definition and were laboratory case-confirmed with COVID-19. Patients were clinically and paraclinically investigated according to the WHO Provisional National Clinical Protocol for COVID-19 infection reporting. The data were statistically processed by the Statistics 10 program. Results: Of the 96 patients with COVID-19, 85 (88.54%) reported at least one had a comorbidity. The prevalence of comorbidities was the following: chronic coronary syndromes (40.1%), hypertension (39.7%), diabetes (16.04%), chronic obstructive pulmonary disease (17.3%), malignancy (13.04%), cerebrovascular disease (10.6%), chronic kidney disease (4.3%) and viral hepatitis B (1.8%). Severe cases of the disease were revealed &ndash; 58, medium severity &ndash; 38 cases. All critical cases resulting in death (7.29%) showed comorbidities with respiratory symptoms, as well as with the onset of acute respiratory failure. Conclusions: The elderly, male gender and the presence of comorbidities in patients with COVID-19 determine the severe course of the disease and an increased mortality rate.</p></description>
</descriptions>
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<format>application/pdf</format>
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