Afișare rezultate

Tuberculosis treatment outcomes in Europe: Based on treatment completion, not cure

Dedicoat Martin John12, Gunther Gunar34, Crudu Valeriu56, Duarte Raquel7, Gualano Gina8, Magis-Escurra Cecile9, Rumetshofer Rudolf10, Skrahina Alena11, Spînu Victor12, Tiberi Simon13, Viiklepp Piret14, van Leth Frank15, Lange Christoph G.3161718

3 Research Center Borstel, 5 Institute of Phtysiopneumology „Chiril Draganiuc”, 6 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 10 Otto Wagner Hospital, Vienna, 13 AOVV E. Morelli Reference Hospital for MDR and HIV-TB, Sondalo, 14 National Institute for Health Development, Tallinn, 18 Karolinska Institutet, Stockholm

American Journal of Respiratory and Critical Care Medicine

Nr. 9(196) / 2017 / ISSN 1073-449X

Disponibil online 15 March, 2022. Descarcări-0. Vizualizări-325

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Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries

Ajbani Kanchan K.1, Lin Shou Yean Grace2, Rodrigues Camilla S.1, Noi Autori, Crudu Valeriu3

2 California Department of Public Health, Richmond, 3 Institute of Phtysiopneumology „Chiril Draganiuc”

Antimicrobial Agents and Chemotherapy

Nr. / 2015 / ISSN 0066-4804 /ISSNe 1098-6596

Disponibil online 18 May, 2023. Descarcări-0. Vizualizări-167

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Limited Nosocomial Transmission of Drug-Resistant Tuberculosis, Moldova

Noroc Ecaterina1, Chesov Dumitru23, Merker Matthias34, Groschel Matthias I.P.5, Barilar Ivan43, Dreyer Viola3, Ciobanu Nelly1, Reimann Maja346, Crudu Valeriu1, Lange Christoph G.346

1 Institute of Phtysiopneumology „Chiril Draganiuc”, 2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 3 Research Center Borstel, 5 Charité - University Medicine Berlin,

Emerging Infectious Diseases

Nr. / 2023 / ISSN 1080-6040 /ISSNe 1080-6059

Disponibil online 12 June, 2023. Descarcări-8. Vizualizări-172

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Multidrug-resistant tuberculosis in Europe, 2010-2011

Gunther Gunar12, van Leth Frank3, Alexandru Sofia4, Noi Autori, Barbuţă Raisa5, Crudu Valeriu4, Cernenco Ilie6, Dubceac Vera5

4 Institute of Phtysiopneumology „Chiril Draganiuc”, 5 Balti Clinical Hospital,

Emerging Infectious Diseases

Nr. 3 / 2015 / ISSN 1080-6040 /ISSNe 1080-6059

Disponibil online 28 May, 2023. Descarcări-4. Vizualizări-188

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Emergence of bedaquiline resistance in a high tuberculosis burden country

Chesov Elena1234, Chesov Dumitru134, Maurer Florian P.4, Andres Sonke4, Utpatel Christian4, Barilar Ivan4, Donica Ana2, Reimann Maja345, Niemann Stefan3, Lange Christoph G.2356, Crudu Valeriu2, Heyckendorf Jan345, Merker Matthias34

1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 2 Institute of Phtysiopneumology „Chiril Draganiuc”, 4 Research Center Borstel,

European Respiratory Journal

Nr. / 2022 / ISSN 0903-1936 /ISSNe 1399-3003

Disponibil online 29 June, 2022. Descarcări-0. Vizualizări-346

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Impact of bedaquiline on treatment outcomes of multidrug-resistant tuberculosis in a high-burden country

Chesov Dumitru123, Heyckendorf Jan234, Alexandru Sofia5, Donica Ana5, Chesov Elena12, Reimann Maja23, Crudu Valeriu5, Botnaru Victor1, Lange Christoph G.234

1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 2 Research Center Borstel, 5 Institute of Phtysiopneumology „Chiril Draganiuc”

European Respiratory Journal

Nr. / 2021 / ISSN 0903-1936 /ISSNe 1399-3003

Disponibil online 19 July, 2023. Descarcări-0. Vizualizări-145

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Lack of evidence of isoniazid efficacy for the treatment of MDR/XDR-TB in the presence of the katG 315T mutation

Chesov Dumitru1, Ciobanu Nelly2, Lange Christoph G.3, Schon Thomas4, Heyckendorf Jan3, Crudu Valeriu2

1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 2 Institute of Phtysiopneumology „Chiril Draganiuc”, 3 Research Center Borstel,

European Respiratory Journal

Nr. / 2017 / ISSN 0903-1936 /ISSNe 1399-3003

Disponibil online 8 March, 2022. Descarcări-0. Vizualizări-327

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Treatment outcomes of MDR-TB and HIV co-infection in Europe

Magis-Escurra Cecile1, Gunther Gunar2, Lange Christoph G.2345, Noi Autori, Ciobanu Ana6, Crudu Valeriu6

5 Karolinska Institutet, Stockholm, 6 Institute of Phtysiopneumology „Chiril Draganiuc”

European Respiratory Journal

Nr. / 2017 / ISSN 0903-1936 /ISSNe 1399-3003

Disponibil online 13 February, 2023. Descarcări-0. Vizualizări-228

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High risk and rapid appearance of multidrug resistance during tuberculosis treatment in Moldova

Jenkins Helen Elizabeth12, Crudu Valeriu3, Soltan Viorel3, Ciobanu Ana4, Domente Liliana4, Cohen Ted52

1 Harvard Medical School, Boston, 3 Harvard T H Chan School of Public Health, Boston, 4 Center for Health Policies and Studies, 5 Institute of Phtysiopneumology „Chiril Draganiuc”

European Respiratory Journal

Nr. / 2014 / ISSN 0903-1936 /ISSNe 1399-3003

Disponibil online 20 July, 2023. Descarcări-0. Vizualizări-164

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Assessing spatial heterogeneity of multidrug-resistant tuberculosis in a high-burden country

Jenkins Helen Elizabeth12, Pleşca Valeriu3, Ciobanu Anisoara3, Crudu Valeriu4, Galusca Irina3, Soltan Viorel4, Serbulenco Aliona5, Zignol Matteo6, Dadu Andrei7, Masoud Dara7, Cohen Ted28

1 Harvard Medical School, Boston, 4 Center for Health Policies and Studies, 6 World Health Organization, 8 Harvard T H Chan School of Public Health, Boston

European Respiratory Journal

Nr. / 2013 / ISSN 0903-1936 /ISSNe 1399-3003

Disponibil online 20 July, 2023. Descarcări-0. Vizualizări-179

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Failing treatment of multidrug-resistant tuberculosis: a matter of definition

Chesov Dumitru1, Alexandru Sofia1, Crudu Valeriu2, Ciobanu Nelly3, Botnaru Victor1, Heyckendorf Jan45, Lange Christoph G.45

1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 2 Institute of Phtysiopneumology „Chiril Draganiuc”, 3 Academy of Sciences of Moldova, 5 Research Center Borstel

International Journal of Tuberculosis and Lung Disease

Nr. 4(23) / 2019 / ISSN 1027-3719 /ISSNe 1815-7920

Disponibil online 28 May, 2019. Descarcări-0. Vizualizări-852

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MDR-TB in Eastern Europe in the era of the TB elimination action framework

Dudnyk Andrii1, Butov Dmytro2, Crudu Valeriu34, Lange Christoph G.4567, Chesov Dumitru4

1 National Pirogov Memorial Medical University, Vinnytsya, 3 Institute of Phtysiopneumology „Chiril Draganiuc”, 4 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 5 Research Center Borstel, 7 Karolinska Institutet, Stockholm

International Journal of Tuberculosis and Lung Disease

Nr. 1(21) / 2017 / ISSN 1027-3719 /ISSNe 1815-7920

Disponibil online 16 March, 2022. Descarcări-0. Vizualizări-227

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Rapid drug susceptibility testing of drug-resistant mycobacterium tuberculosis isolates directly from clinical samples by use of amplicon sequencing: A proof-of-concept study

Colman Rebecca E.1, Anderson Julia1, Lemmer Darrin1, Lehmkuhl Erik1, Georghiou Sophia B.2, Heaton Hannah1, Wiggins Kristin B.1, Gillece John D.1, Schupp James M.1, Catanzaro Donald G.3, Crudu Valeriu4, Cohen Ted5, Rodwell Timothy C.2, Engelthaler David M.1

1 Translational Genomics Research Institute, Flagstaff, AZ, 2 University of San Diego, 3 University of Arkansas, 4 Institute of Phtysiopneumology „Chiril Draganiuc”, 5 Yale School of Public Health, New Haven

Journal of Clinical Microbiology

Nr. 8(54) / 2016 / ISSN 0095-1137 /ISSNe 1098-660X

Disponibil online 2 August, 2022. Descarcări-0. Vizualizări-300

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MTBDRplus and MTBDRsl Assays: Absence of wild-type probe hybridization and implications for detection of drug-resistant tuberculosis

Seifert Marva1, Georghiou Sophia B.1, Catanzaro Donald G.2, Rodrigues Camilla S.3, Crudu Valeriu4, Victor Thomas Calldo5, Garfein Richard S.1, Catanzaro Antonino1, Rodwell Timothy C.1

2 University of Arkansas, 4 Institute of Phtysiopneumology „Chiril Draganiuc”, 5 Stellenbosch University, Cape Town

Journal of Clinical Microbiology

Nr. 4(54) / 2016 / ISSN 0095-1137 /ISSNe 1098-660X

Disponibil online 17 January, 2023. Descarcări-0. Vizualizări-199

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The recent rapid expansion of multidrug resistant Ural lineage Mycobacterium tuberculosis in Moldova

Chitwood Melanie H.1, Colijn Caroline2, Yang Chongguang3, Crudu Valeriu4, Ciobanu Nelly4, Codreanu Alexandru4, Kim Jae Hee5, Rancu Isabel1, Rhee Kyu Y.6, Cohen Ted1, Sobkowiak Benjamin1

1 Yale School of Public Health, New Haven, 3 Yat-sen University, Shenzhen, 4 Institute of Phtysiopneumology „Chiril Draganiuc”, 6 Weill Cornell Medicine, New York

Nature Communications

Nr. / 2024 / ISSN 2041-1723

Disponibil online 22 April, 2024. Descarcări-1. Vizualizări-27

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Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

Stucki David 1, Brites Daniela1, Jeljeli Leila 2, Coscolla Mireia1, Liu Qingyun3, Trauner Andrej1, Fenner Lukas 4, Rutaihwa Liliana Kokusanilwa1, Borrell Sonia5, Luo Tao6, Gao Qian 3, Kato-Maeda Midori7, Ballif Marie 8, Egger Matthias 9, Macedo Rita 10, Mardassi Helmi11, Moreno Milagros12, Vilanova Griselda Tudo13, Fyfe Janet A.M.14, Globan Maria14, Thomas Jackson4, Jamieson Frances B15, Guthrie Jennifer L16, Asante-Poku Adwoa17, Yeboah-Manu Dorothy17, Wampande Eddie M.18, Ssengooba Willy19, Joloba Moses Lutaakome19, Boom Henry Henry20, Basu Indira21, Bower James E.21, Saraiva Margarida22, Vasconcellos Sidra Ezidio Goncalves23, Suffys Philip Noel Oel23, Koch Anastasia S.24, Wilkinson Robert25, Gail-Bekker Linda24, Malla Bijaya 1, Ley Serej 1, Beck Hans Peter1, De Jong Bouke C.26, Toit Kadri27, Sanchez-Padilla Elisabeth28, Bonnet Maryline28, Gil-Brusola Ana29, Frank Matthias30, Penlap Beng Veronique N.31, Eisenach Kathleen D.32, Al-Ani Issam 33, Ndung'U Perpetual Wangui34, Revathi Gunturu35, Gehre Florian36, Akter Suriya26, Ntoumi Francine37, Stewart-Isherwood Lynsey38, Ntinginya Nyanda Elias39, Rachow Andrea40, Hoelscher Michael41, Cirillo Daniela42, Skenders Girts43, Hoffner Sven Erik 44, Bakonyte Daiva45, Stakenas Petras45, Diel Roland46, Moldovan Olga47, Crudu Valeriu48, Al-Hajoj Sahal Abdulaziz M.49, Otero Larissa49, Barletta Francesca50, Carter E. Jane51, Diero Lameck O.52, Supply Philip53, Comas I.54, Niemann Stefan2, Gagneux Sebastien P.27

2 Research Center Borstel, 5 University of Basel, 9 University of Bern, 31 University of Yaoundé I, 45 Vilnius University, 48 Institute of Phtysiopneumology „Chiril Draganiuc”, 49 Peruvian University Cayetano Heredia, Lima, 50 Brown University, 53 Universitat de València,

Nature Genetics

Nr. / 2016 / ISSN 1061-4036 /ISSNe 1546-1718

Disponibil online 6 November, 2017. Descarcări-0. Vizualizări-732

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Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

Merker Matthias1, Blin Camille23, Mona Stefano23, Noi Autori, Crudu Valeriu4

1 Research Center Borstel, 2 Practical School of Advanced Studies, Paris, 4 Institute of Phtysiopneumology „Chiril Draganiuc”

Nature Genetics

Nr. 3 / 2015 / ISSN 1061-4036 /ISSNe 1546-1718

Disponibil online 19 May, 2023. Descarcări-0. Vizualizări-221

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Performance comparison of three rapid tests for the diagnosis of drug-resistant tuberculosis

Catanzaro Antonino1, Rodwell Timothy C.1, Catanzaro Donald G.2, Noi Autori, Crudu Valeriu3

2 University of Arkansas, 3 Institute of Phtysiopneumology „Chiril Draganiuc”

PLoS ONE

Nr. / 2015 / ISSN 1932-6203

Disponibil online 6 June, 2023. Descarcări-4. Vizualizări-186

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Detection of low-level mixed-population drug resistance in Mycobacterium tuberculosis using high fidelity amplicon sequencing

Colman Rebecca E.1, Schupp James M.1, Hicks Nathan D.1, Smith David Earl1, Buchhagen Jordan L.1, Valafar Faramarz2, Crudu Valeriu3, Romancenco Elena4, Noroc Ecaterina3, Jackson Lynn4, Catanzaro Donald G.5, Rodwell Timothy C.4, Catanzaro Antonino4, Keim Paul S.6, Engelthaler David M.1

1 Translational Genomics Research Institute, Flagstaff, AZ, 2 San Diego State University, 3 Institute of Phtysiopneumology „Chiril Draganiuc”, 5 University of Arkansas, 6 Northern Arizona University, Flagstaff

PLoS ONE

Nr. 5 / 2015 / ISSN 1932-6203

Disponibil online 10 May, 2023. Descarcări-0. Vizualizări-173

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Combined antigen-specific interferon-γ and interleukin-2 release assay (FluoroSpot) for the diagnosis of Mycobacterium tuberculosis infection

Chesov Dumitru12, Lange Christoph G.2, Daduna Franziska23, Crudu Valeriu4, Preyer Rosemarie5, Ernst Martin2, Kalsdorf Barbara6

1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy, 2 Research Center Borstel, 3 German Center for Infection Research, Tuberculosis Unit, Borstel, 4 Institute of Phtysiopneumology „Chiril Draganiuc”, 5 Autoimmun diagnostics GmbH, Strassberg, 6 Research Center Boreal

PLoS ONE

Nr. 3 / 2015 / ISSN 1932-6203

Disponibil online 5 May, 2023. Descarcări-0. Vizualizări-132

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