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Ciobanu Nelly14Alexandru Sofia9Chesov Dumitru8Ţurcan Nadejda6Lange Christoph G.6Moraru Nicolae5Noroc (Stratan) Ecaterina5Codreanu Alexandru5Gulea Aurelian4Macaev Fliur4Sain Dumitru4Ţapcov Victor4Romancenco Elena4Heyckendorf Jan4Cohen Ted4Cotelea Tamara3Valica Vladimir3Uncu Livia3Soltan Viorel3Vîlc Valentina3Morusceag Laurentiu3Bivol Stela3Niţulescu George-Mihai3Eftodii Sergiu3Chesov Elena3Rosenthal Alex3Harris Michael3Catanzaro Donald G.3Colijn Caroline3Iavorschi Constantin2Rudic Valeriu2Bîrcă Maria2Rîvneac Lidia2Sucman Natalia2Haidarlî Ion2Cotovaia Aliona2Stingaci Eugenia2Lesan Victor2Nepoliuc Liubovi2Petrica Victoria2Chiriţa Ileana-Cornelia2Niemann Stefan2Eldholm Vegard2Brynildsrud Ola Bronstad2Gabrielian Andrei E.2Hurt Darrell E.2Wollenberg Kurt R.2Tartakovsky Michael2Taaffe Jessica E.2Long Alyssa2Akhundova Irada2Vashakidze Sergo2Skrahina Alena2Spînu Victor2Hillery Naomi2Rodwell Timothy C.2Catanzaro Antonino2Rodrigues Camilla S.2Gunther Gunar2Stimson James2Mathema Barun2Noroc Ecaterina2Menzies Nicolas A.2Fosburgh Heather2Drumea Maria2Gudumac Valentin1Ciumacov Iurie1Petrenko Piotr1Bulimaga Valentina1Chiriac Tatiana1Cotici Alexandru1Vorojbit Valentina1Bivol Grigore1Brumaru Albina1Burlacu Valeriu1Chiroşca Valentina1Crivenco Galina1Jurja Larisa1Privalova Elena1Botnaru Victor1Diug Eugen1Ghinda Serghei1Godoroja Pavel1Nicolau Gheorghe1Sofronie Silviu1Tudos Tamara1Ustian Aurelia1Zveaghinţeva Marina1Ciobanu Nellu1Marusceac Irina1Golişceva Olga1Boldescu Veaceslav1Pogrebnoi Serghei1Postolati Natalia1Uncuţa Diana1Nalivaico Nicolae1Talpă Oleg1Tuzicov Alexandr1Ciobanu Sergiu1Popa Mariana1Gulea Alexandru1Burinschi Victor1Darii Victoria1Baltag Lilian1Niguleanu Adriana1Munteanu Mariana1Ţîmbalari Vitalie1Maximenco Anna1Malic Alina1Ciobanu Ana1Graur Vasile1Cirillo Daniela1Seicaş Rita1Melnic S.1Balteanu L.1Corloteanu Andrei1Buga Alexandru1Serbulenco Aliona1Barbuţă Raisa1Pogrebnoi Vsevolod1Rush-Gerdes Sabine1Moşneaga Andrei1Allerheiligen Vera1Hillemann Andreas1Bogdan V.1Garbuz Olga1Balan Greta1Lesnic Evelina1Malic Elena1Smaglii Vadim1Domente Liliana1Chiriţă Cornel1Ronning Janne O1Mengshoel Anne Torunn Orunn1Debech Nadia1Bohlin Jon1Pettersson John H.O1Kitchen Andrew1Rasmussen Erik1Lillebaek Troels1Alfsnes Kristian1Pepperell Caitlin1Balloux Francois1Stucki David 1Brites Daniela1Coscolla Mireia1Trauner Andrej1Rutaihwa Liliana Kokusanilwa1Malla Bijaya 1Ley Serej 1Beck Hans Peter1Jeljeli Leila 1Liu Qingyun1Gao Qian 1Borrell Sonia1Egger Matthias 1Ssengooba Willy1Joloba Moses Lutaakome1Stakenas Petras1Bakonyte Daiva1Supply Philip1Barletta Francesca1Macedo Rita 1Jamieson Frances B1Fenner Lukas 1Luo Tao1Kato-Maeda Midori1Ballif Marie 1Mardassi Helmi1Moreno Milagros1Vilanova Griselda Tudo1Fyfe Janet A.M.1Globan Maria1Guthrie Jennifer L1Asante-Poku Adwoa1Yeboah-Manu Dorothy1Wampande Eddie M.1Boom Henry Henry1Basu Indira1Bower James E.1Saraiva Margarida1Vasconcellos Sidra Ezidio Goncalves1Suffys Philip Noel Oel1Koch Anastasia S.1Wilkinson Robert1Gail-Bekker Linda1De Jong Bouke C.1Akter Suriya1Toit Kadri1Sanchez-Padilla Elisabeth1Bonnet Maryline1Gil-Brusola Ana1Frank Matthias1Penlap Beng Veronique N.1Eisenach Kathleen D.1Al-Ani Issam 1Ndung'U Perpetual Wangui1Revathi Gunturu1Gehre Florian1Ntoumi Francine1Stewart-Isherwood Lynsey1Ntinginya Nyanda Elias1Rachow Andrea1Skenders Girts1Hoffner Sven Erik 1Diel Roland1Al-Hajoj Sahal Abdulaziz M.1Otero Larissa1Carter E. Jane1Diero Lameck O.1Comas I.1Gagneux Sebastien P.1Thomas Jackson1Hoelscher Michael1Moldovan Olga1Engle Eric1Sergueev Eugene1Kirichenko Valery1Lapitskii Vladzimir1Snezhko Eduard1Kovalev Vassili1Ismayilova Sharafat1Mammadbayov Elcan1Gadirova Hagigat1Abuzarov Rafik1Seyfaddinova Mehriban1Avaliani Zaza1Shubladze Natalia1Nanava Ucha1Astrovko Andrei1Skrahin Aliaksandr1Strâmbu Irina Ruxandra1Zaharia Dragoş C.1Muntean Alexandru A.1Ghita Eugenia1Bogdan Miron Alexandru1Mîndru Roxana1Sora Alexandra1Ene Catalina1Dedicoat Martin John1Duarte Raquel1Dudnyk Andrii1Groessl E. J.1Ganiats Theodore G.1Jackson Roberta L.1Garfein Richard S.1Victor Thomas Calldo1Trollip Andre Phillip1Racoviță Stela1Şișcanova N.1Vesga Juan Fernando1Celan Cristina1Gardy Jennifer L.1Somoskovi Akos1Czoboly N.1Kiss D.1Cuevas Luis Eduardo1Butov Dmytro1Cates L.1Santos Victor Santana1Goletti Delia1Reid Michael J.A.1Arinaminpathy Nimalan1Seifert Marva1McKinnon Symone1Colman Rebecca E.1Chiles Peter G.1Hagan Christopher1Brown Tyler S.1Osnes Magnus N.1Levy Natalie1Merker Matthias1Penn-Nicholson Adam1Georghiou Sophia B.1Kazi Mubin I.1Bhalla Manpreet1David Anura1Conradie Francesca1Ruhwald Morten1Myneedu Vithal Prasad1Scott Lesley1Denkinger Claudia M.1Schumacher Samuel G.1Schon Thomas1Gualano Gina1Magis-Escurra Cecile1Rumetshofer Rudolf1Tiberi Simon1Viiklepp Piret1van Leth Frank1Yang Chongguang1Sobkowiak Benjamin1Naidu Vijay1Gunasekera Kenneth S.1Chitwood Melanie H.1Russi Marcus1Havumaki Joshua S.1Cudahy Patrick George Tobias1Allender Christopher J.1Centner Heather1Engelthaler David M.1Warren Joshua L.1Kheirandish Maryam1Zhang Shengfan1Marin Maximillian G.1Vargas Roger1Epperson L. Elaine1Durbin David1Strong Michael1Salfinger Max1Iqbal Zamin1Farhat Maha Reda1Jeffrey Brendan1
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Articole în reviste din RM - 21. Publicaţii la conferinţe din RM - 5. Publicaţii peste hotare - 24.
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2022 - 4

Benchmarking the empirical accuracy of short-read sequencing across the M. tuberculosis genome
Marin Maximillian G.1 , Vargas Roger1 , Harris Michael2 , Jeffrey Brendan3 , Epperson L. Elaine3 , Durbin David3 , Strong Michael3 , Salfinger Max4 , Iqbal Zamin5 , Akhundova Irada6 , Vashakidze Sergo7 , Crudu Valeriu89 , Rosenthal Alex2 , Farhat Maha Reda10
1 Harvard Medical School, Boston,
2 National Institute of Allergy and Infectious Diseases, Department of Health and Human Services, Bethesda,
3 National Jewish Health, Denver,
4 University of South Florida,
5 European Bioinformatics Institute (EMBL-EBI), Hinxton,
6 Scientific Research Institute of Lung Diseases, Ministry of Health, Baku,
7 National Center for Tuberculosis and Lung Diseases, Tbilisi,
8 Institute of Phtysiopneumology „Chiril Draganiuc”,
9 Ministerul Sănătăţii a Republicii Moldova,
10 Massachusetts General Hospital, Boston
Bioinformatics
Nr. 7(38) / 2022 / ISSN 1367-4803 / ISSNe 1367-4811
Disponibil online 23 May, 2022. Descarcări-0. Vizualizări-4
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Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre diagnostic accuracy study
Penn-Nicholson Adam1 , Georghiou Sophia B.1 , Ciobanu Nelly2 , Kazi Mubin I.3 , Bhalla Manpreet4 , David Anura5 , Conradie Francesca5 , Ruhwald Morten1 , Crudu Valeriu2 , Rodrigues Camilla S.6 , Myneedu Vithal Prasad4 , Scott Lesley5 , Denkinger Claudia M.71 , Schumacher Samuel G.1
1 FIND, Geneva,
2 Institute of Phtysiopneumology „Chiril Draganiuc”,
3 Hinduja Hospital and Research Centre, Mumbai,
4 National Institute of TB and Respiratory Diseases, New Delhi,
5 University of Witwatersrand,
6 Hinduja National Hospital, Mumbai,
7 University Hospital Heidelberg
The Lancet Infectious Diseases
Nr. 2(22) / 2022 / ISSN 1473-3099 / ISSNe 1474-4457
Disponibil online 6 February, 2022. Descarcări-0. Vizualizări-57
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Integrating landmark modeling framework and machine learning algorithms for dynamic prediction of tuberculosis treatment outcomes
Kheirandish Maryam1 , Catanzaro Donald G.1 , Crudu Valeriu23 , Zhang Shengfan1
1 University of Arkansas,
2 Institute of Phtysiopneumology „Chiril Draganiuc”,
3 ”Nicolae Testemițanu” State University of Medicine and Pharmacy
Journal of the American Medical Informatics Association
Nr. 5(29) / 2022 / ISSN 1067-5027 / ISSNe 1527-974X
Disponibil online 20 May, 2022. Descarcări-0. Vizualizări-22
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RESEARCH ARTICLE Phylogeography and transmission of M. tuberculosis in Moldova: A prospective genomic analysis
Yang Chongguang1 , Sobkowiak Benjamin2 , Naidu Vijay2 , Codreanu Alexandru3 , Ciobanu Nelly3 , Gunasekera Kenneth S.4 , Chitwood Melanie H.4 , Alexandru Sofia3 , Bivol Stela5 , Russi Marcus4 , Havumaki Joshua S.4 , Cudahy Patrick George Tobias4 , Fosburgh Heather4 , Allender Christopher J.6 , Centner Heather6 , Engelthaler David M.6 , Menzies Nicolas A.7 , Warren Joshua L.4 , Crudu Valeriu3 , Colijn Caroline2 , Cohen Ted8
1 Yat-sen University, Shenzhen,
2 Simon Fraser University,
3 Institute of Phtysiopneumology „Chiril Draganiuc”,
4 Yale School of Public Health, New Haven,
5 Centrul pentru Politici şi Analize în Sănătate (Centrul PAS),
6 Translational Genomics Research Institute, Flagstaff, AZ,
7 Harvard T H Chan School of Public Health, Boston,
8 Yale University, Connecticut
PLoS Medicine
Nr. 2(19) / 2022 / ISSN 1549-1277
Disponibil online 17 March, 2022. Descarcări-0. Vizualizări-56
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2021 - 9

Evaluarea activității antifungice și antibacteriene a unui nou derivat nesaturat de 1,2,4-triazol (Nitrotriazon).
Drumea Maria1 , Stingaci Eugenia2 , Uncu Livia1 , Crudu Valeriu3 , Valica Vladimir1 , Macaev Fliur12
1 Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“,
2 Institutul de Chimie,
3 IMSP Institutul de Ftiziopneumologie „Chiril Draganiuc“
Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţe Medicale
Nr. 1(69) / 2021 / ISSN 1857-0011
Disponibil online 1 June, 2021. Descarcări-4. Vizualizări-224
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Evolution and emergence of multidrug-resistant Mycobacterium tuberculosis in Chisinau, Moldova
Brown Tyler S.1 , Eldholm Vegard2 , Brynildsrud Ola Bronstad2 , Osnes Magnus N.2 , Levy Natalie3 , Stimson James4 , Colijn Caroline5 , Alexandru Sofia6 , Noroc Ecaterina6 , Ciobanu Nelly6 , Crudu Valeriu6 , Cohen Ted7 , Mathema Barun3
1 Massachusetts General Hospital, Boston,
2 Norwegian Institute of Public Health,
3 Columbia University, New York,
4 Public Health England,
5 Simon Fraser University,
6 Institute of Phtysiopneumology „Chiril Draganiuc”,
7 Yale University, Connecticut
Microbial Genomics
Nr. 8(7) / 2021 / ISSN 2057-5858
Disponibil online 27 September, 2021. Descarcări-0. Vizualizări-94
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Genetic mutations associated with reduced linezolid sussceptibility of mycobacterium tuberculosis strains
Chesov Elena12 , Ciobanu Nelly2 , Crudu Valeriu2
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Institute of Phtysiopneumology „Chiril Draganiuc”
Cercetarea în biomedicină și sănătate: calitate, excelență și performanță
2021. Chișinău, Republica Moldova. ISBN 978-9975-82-223-7 (PDF)..
Disponibil online 7 December, 2021. Descarcări-0. Vizualizări-50
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Laboratory costs of diagnosing TB in a high multidrug-resistant TB setting
Cates L.1 , Crudu Valeriu23 , Codreanu Alexandru2 , Ciobanu Nellu23 , Fosburgh Heather4 , Cohen Ted4 , Menzies Nicolas A.1
1 Harvard T H Chan School of Public Health, Boston,
2 Institute of Phtysiopneumology „Chiril Draganiuc”,
3 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
4 Yale University, Connecticut
The international journal of tuberculosis and lung disease
Nr. 3(25) / 2021 / ISSN 1815-7920
Disponibil online 30 March, 2021. Descarcări-0. Vizualizări-120
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Nivelul de rezistență fenotipică și paternul de mutații genice a M. tuberculosis.
Ciobanu Nelly , Codreanu Alexandru , Ţurcan Nadejda , Noroc Ecaterina , Crudu Valeriu
IMSP Institutul de Ftiziopneumologie „Chiril Draganiuc“
Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţe Medicale
Nr. 1(69) / 2021 / ISSN 1857-0011
Disponibil online 1 June, 2021. Descarcări-1. Vizualizări-121
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Perspectives for use of a new unsaturated derivative of 1,2,4–triazol with antifungal and antibacterial action–nitrotriazone
Drumea Maria1 , Valica Vladimir1 , Uncu Livia1 , Makaev F.2 , Crudu Valeriu3
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Institutul de Chimie,
3 Institute of Phtysiopneumology „Chiril Draganiuc”
Cercetarea în biomedicină și sănătate: calitate, excelență și performanță
2021. Chișinău, Republica Moldova. ISBN 978-9975-82-223-7 (PDF)..
Disponibil online 16 December, 2021. Descarcări-0. Vizualizări-235
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Rapid detection of extensively drug-resistant tuberculosis in clinical samples using a novel tabletop platform: Protocol for a prospective clinical study
Hillery Naomi1 , Seifert Marva1 , Catanzaro Donald G.2 , McKinnon Symone1 , Colman Rebecca E.1 , Chiles Peter G.1 , Chesov Dumitru34 , Ciobanu Nelly35 , Hagan Christopher1 , Crudu Valeriu35 , Catanzaro Antonino1 , Rodwell Timothy C.1
1 University of California, San Diego,
2 University of Arkansas,
3 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
4 Research Center Borstel,
5 Institute of Phtysiopneumology „Chiril Draganiuc”
JMIR Research Protocols
Nr. 7(10) / 2021 / ISSN - / ISSNe 1929-0748
Disponibil online 3 August, 2021. Descarcări-0. Vizualizări-141
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Rezistenţa Mycobacterium tuberculosis la Linezolid – mutaţii asociate și factori de risc: studiu transversal, retrospectiv, analitic
Chesov Elena123 , Ciobanu Nelly21 , Chesov Dumitru134 , Lange Christoph G.4356 , Heyckendorf Jan435 , Merker Matthias4 , Crudu Valeriu12
1 Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“,
2 IMSP Institutul de Ftiziopneumologie „Chiril Draganiuc“,
3 Centrul German pentru Cercetarea Infecţiilor (DZIF), Partner site Hamburg- Lübeck-Borstel-Riems,
4 Centrul de Cercetare din Borstel,
5 Universitatea din Lubeck,
6 Colegiul de Medicină Baylor
Revista de Ştiinţe ale Sănătăţii din Moldova
Nr. 1(26) / 2021 / ISSN 2345-1467
Disponibil online 17 November, 2021. Descarcări-2. Vizualizări-61
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Studiul activităţii antituberculoase a particulelor de ciclodextrine încărcate cu juglonă
Сукман Наталья12 , Uncu Livia2 , Crudu Valeriu3 , Ciobanu Nelly3 , Codreanu Alexandru3 , Valica Vladimir2 , Macaev Fliur21
1 Institutul de Chimie,
2 Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“,
3 IMSP Institutul de Ftiziopneumologie „Chiril Draganiuc“
Revista Farmaceutică a Moldovei
Nr. 1(45) / 2021 / ISSN 1812-5077
Disponibil online 21 September, 2021. Descarcări-2. Vizualizări-182
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2020 - 3

A retrospective genomic analysis of drug-resistant strains of M. tuberculosis in a high-burden setting, with an emphasis on comparative diagnostics and reactivation and reinfection status
Wollenberg Kurt R.1 , Harris Michael1 , Gabrielian Andrei E.1 , Ciobanu Nelly2 , Chesov Dumitru34 , Long Alyssa1 , Taaffe Jessica E.1 , Hurt Darrell E.1 , Rosenthal Alex1 , Tartakovsky Michael1 , Crudu Valeriu2
1 National Institute of Allergy and Infectious Diseases, Department of Health and Human Services, Bethesda,
2 Institute of Phtysiopneumology „Chiril Draganiuc”,
3 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
4 Research Center Borstel
BMC Infectious Diseases
Nr. 1(20) / 2020 / ISSN 1471-2334
Disponibil online 27 January, 2020. Descarcări-1. Vizualizări-497
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Automated high-throughput digital fluorescence microscopy for TB diagnosis
Chesov Dumitru1 , Lesanu Victor2 , Ciobanu Nelly2 , Codreanu Alexandru2 , Crudu Valeriu2 , Cuevas Luis Eduardo3 , Kiss D.4 , Czoboly N.4 , Somoskovi Akos5
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Institute of Phtysiopneumology „Chiril Draganiuc”,
3 Liverpool School of Tropical Medicine,
4 Necunoscută, Ungaria,
5 Roche Molecular Systems Inc, Pleasanton
The international journal of tuberculosis and lung disease
Nr. 10(24) / 2020 / ISSN 1815-7920
Disponibil online 10 November, 2020. Descarcări-0. Vizualizări-234
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Sinteza, proprietăţile fizico-chimice, antioxidative și antituberculoase ale compușilor coordinativi ai unor metale 3d cu izonicotinoilhidrazona 2-hidroxi-3-metoxibenzaldehida
Bîrcă Maria1 , Cotovaia Aliona1 , Ţapcov Victor1 , Garbuz Olga1 , Crudu Valeriu2 , Gulea Aurelian1
1 Universitatea de Stat din Moldova,
2 IMSP Institutul de Ftiziopneumologie „Chiril Draganiuc“
Studia Universitatis Moldaviae (Seria Ştiinţe Reale şi ale Naturii)
Nr. 6(136) / 2020 / ISSN 1814-3237 / ISSNe 1857-498X
Disponibil online 22 January, 2021. Descarcări-31. Vizualizări-325
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2019 - 6

Acute phase proteins and IP-10 as triage tests for the diagnosis of tuberculosis: systematic review and meta-analysis
Santos Victor Santana1 , Goletti Delia2 , Crudu Valeriu3
1 Federal University of Alagoas, Arapiraca,
2 ‘L. Spallanzani’ National Institute for Infectious Diseases (INMI), Rome,
3 Institute of Phtysiopneumology „Chiril Draganiuc”
Clinical Microbiology and Infection
Nr. 2(25) / 2019 / ISSN 1198-743X / ISSNe 1469-0691
Disponibil online 28 April, 2021. Descarcări-0. Vizualizări-171
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Assessing tuberculosis control priorities in high-burden settings: a modelling approach
Vesga Juan Fernando1 , Alexandru Sofia2 , Vîlc Valentina2 , Crudu Valeriu2 , Bivol Stela3 , Celan Cristina4
1 Imperial College London,
2 Institute of Phtysiopneumology „Chiril Draganiuc”,
3 Centrul pentru Politici şi Analize în Sănătate (Centrul PAS),
4 Center for Health Policies and Studies (PAS)
The Lancet Global Health
Nr. 5(7) / 2019 / ISSN 2214-109X
Disponibil online 22 April, 2019. Descarcări-0. Vizualizări-493
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Beyond the SNP Threshold: Identifying Outbreak Clusters Using Inferred Transmissions
Stimson James1 , Gardy Jennifer L.2 , Mathema Barun3 , Crudu Valeriu4 , Cohen Ted5 , Colijn Caroline1
1 Imperial College London,
2 British Columbia Centre for Disease Control,
3 Columbia University, New York,
4 Institute of Phtysiopneumology „Chiril Draganiuc”,
5 Yale University, Connecticut
Molecular Biology and Evolution
Nr. 3(36) / 2019 / ISSN 0737-4038
Disponibil online 27 March, 2019. Descarcări-0. Vizualizări-402
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Building a tuberculosis-free world: The Lancet Commission on tuberculosis
Reid Michael J.A.1 , Arinaminpathy Nimalan2 , Alexandru Sofia3 , Crudu Valeriu4
1 University of California, San Francisco,
2 University College London,
3 Institute of Phtysiopneumology „Chiril Draganiuc”,
4 National Center of Public Health
The Lancet
Nr. 393(10178) / 2019 / ISSN 0140-6736
Disponibil online 3 May, 2021. Descarcări-0. Vizualizări-101
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