Inductively coupled plasma mass spectrometry (ICP-MS) is an optical technique currently used in elemental analysis in many diverse research fields such as life, environmental, earth, forensic sciences and in food, chemical, material and nuclear industries. The technique has many advantages over other techniques such as the Flame-AAS, GF-AAS, and ICP-AES. The main advantages compared to the other techniques are higher analytical speed, higher sensitivity, lower limits, multi-element, trace analysis and analysis of rare-earth elements. The different types of analysis are quantitative, semiquantitative, isotope ratio and isotope dilution. Quantitative analysis (Full Quant Analysis) gives the exact quantitative results of the element under investigation with all the necessary statistical data to ensure the quality and accuracy of the analysis. Semi-quantitative analysis gives the concentration of all the elements of the periodic table that a sample contains with approximate concentrations of each element ±30% in just a few minutes. It provides a fingerprint of the elements present in a sample. Acknowledgement: We acknowledge the funding from ENI project eMS code BSB27 MONITOX (2018-2021), Joint Operational Programme Black Sea Basin 2014-2020.