Rolul speciilor reactive ale oxigenului şi statusul antiperoxidic în infecţiile de tract urinar în uropatiile malformative la copil
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BERNIC, Jana; CURAJOS, Boris; DZERO, Vera; ROLLER, Victor; CURAJOS, Anatol; CELAC, Victoria; ZAHARIA, Ion; GHEŢEUL, Eugen; REVENCO, Ina; MALANCO, Serghei. Rolul speciilor reactive ale oxigenului şi statusul antiperoxidic în infecţiile de tract urinar în uropatiile malformative la copil. In: Analele Ştiinţifice (Asociaţia Chirurgilor Pediatri Universitari din RM) . 2009, nr. XI, pp. 46-51. ISSN 1857-0631.
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Analele Ştiinţifice (Asociaţia Chirurgilor Pediatri Universitari din RM)
Numărul XI / 2009 / ISSN 1857-0631

Rolul speciilor reactive ale oxigenului şi statusul antiperoxidic în infecţiile de tract urinar în uropatiile malformative la copil

Pag. 46-51

Bernic Jana, Curajos Boris, Dzero Vera, Roller Victor, Curajos Anatol, Celac Victoria, Zaharia Ion, Gheţeul Eugen, Revenco Ina, Malanco Serghei
 
 
Disponibil în IBN: 14 decembrie 2013


Rezumat

The work purpose consists in biochemical monitoring in blood serum and erythrocytes of the lipid hydroperoxides, malonic dialdehyde in congenital anomalies of reno-urinary system complicated with reno-urinary infection in children. The analysis of complex clinical and paraclinical exams of 304 patients by the age of 0-18 years is carried out. Authentic changes of reactive species of oxygen and their inhibitors which was characterized by increasing of diene conjugate and malonic dialdehyde concentrations in comparison with the system of antioxidant protection are revealed and tactics of pathogenic treatment was elaborated.

Цель работы состоит в биохимическом мониторинге в сыворотке крови и эритроцитах содержания гидроперекисей липидов, малонового диальдегида при врожденных уропатиях у детей осложненные инфекцией мочевыделительного тракта. Проведен анализ комплексного клинического и параклинического обследования у 304 пациентов в возрасте 0-18 лет. Выявлены достоверные изменения реактивных специй организма и их ингибиторов характеризующиеся увеличением уровня диеновых коньюгат и малонового диальдегида по сравнению с системой антиоксидантной защиты и выработана тактика патогенетического лечения.

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