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SM ISO690:2012 TOFAN-SCUTARU, Liudmila, CERVINSKI, Irina, DUMBRAVA, Vlada-Tatiana, LUPAŞCO, Iulianna, TARAN, Natalia, BERLIBA, Elina, ŢURCAN, Svetlana, PROCA, Nicolae, MOSCALU, Iurie, ŢURCANU, Adela, COBÎLTEAN, Lucia, CHIRVAS, Elena, HAREA, Gheorghe, COJUHARI, Maria, GANEA, Cătălin. Manifestările clinico-paraclinice și factorii precipitanți ai insufi cienței hepatice cronice din ciroza hepatică. In: Sănătate Publică, Economie şi Management în Medicină , 2013, nr. 5(50), pp. 165-173. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | |||
Numărul 5(50) / 2013 / ISSN 1729-8687 /ISSNe 2587-3873 | |||
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Pag. 165-173 | |||
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The study group included 80 patients with liver cirrhosis (LC), Child-Pugh stage B and C average age 54.95 ± 1.09 years, with chronic liver failure (CLF). Lot of comparison – and 21 patients with liver cirrhosis, Child-Pugh stage A. Clinical manifestations in patients with liver cirrhosis Child-Pugh stage B and C with chronic liver failure, shows polymorphism; there were found basic clinical syndromes: ascites (91.3%), jaundice (88.7%), bleeding (53.8%), fever (47.5%), endocrine (9%), of cardiovascular disorders (30%). We established the base of the CLF precipitating factors: alcohol (45%), spontaneous bacterial peritonitis (23.8%), respiratory infections and / or urinary infections (18.8%), upper gastrointestinal bleeding (20%) misuse of food proteins (20%). Reliable correlations were determined between respiratory infections and / or urinary infections with Child-Pugh score and MELD score. We determined the presence of multiple precipitating factors and also established correlation between the values MELD score with number precipitating factors of CLF from LC. In patients with LC with CLF it was established true positive correlation of the hepatodepressive syndrome indices studied each and with serum Na+ and negative correlation with the degree of ascites and with Child-Pugh and MELD scores. It was established truthful negative correlation of natriemi with total bilirubin and MELD and Child-Pugh scores, so hyponatremia may serve as a prognostic factor for the development of CLF from LC. |
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Cuvinte-cheie Chronic liver failure, cirrhosis, Child-Pugh, MELD, хроническая печеночная недостаточность, цирроз печени, Child-Pugh, MELD |
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