The oral cavity in dogs and cats as well as other open cavities of the body possess a complex microbiocenosis but, less studied. Generally, in the oral cavity, some comensum germs may become pathogenic opportunists, being the first responsible for the occurrence of oral cavity infections. When pets are involved in aggressive actions against humans, transmission of these microorganisms has an epidemiological impact. The plagues created may sometimes be extremely severe, both by mechanical action on the tissues and organs as well as by the inoculated microorganisms that can cause local infections and systemic complications in humans. The purpose of this study was to identify pathogenic bacterial microflora present in dog and cat wounds to their owners and to the veterinary medical staff in office. From the samples taken from biting wounds and the oral cavity of the aggressive animals, both aerobic bacteria (Staphylococcus aureus, Staphylococcus pseudointermedius, Staphylococcus epidermidis, Streptococcus beta hemolitic, Trueperella pyogenes, Corynebacterium, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa) and anaerobic bacteria (Nocardia asteroides, Clostridium perfringens). In order to guide the therapy, bacterial susceptibility of isolated strains was tested against some antibiotics recommended for the treatment of wounds.