Synthesis, characterization, crystal structure and antimicrobial activity of copper(II) complexes
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2023-10-19 14:45
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BÎRCĂ, Maria, RUSNAC, Roman, BIRSANU, Irina, BALAN, Greta, PETRENKO, Peter A., GULYA, Aurelian. Synthesis, characterization, crystal structure and antimicrobial activity of copper(II) complexes. In: Achievements and perspectives of modern chemistry, 9-11 octombrie 2019, Chişinău. Chisinau, Republic of Moldova: Tipografia Academiei de Ştiinţe a Moldovei, 2019, p. 78. ISBN 978-9975-62-428-2.
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Achievements and perspectives of modern chemistry 2019
Conferința "International Conference "Achievements and perspectives of modern chemistry""
Chişinău, Moldova, 9-11 octombrie 2019

Synthesis, characterization, crystal structure and antimicrobial activity of copper(II) complexes


Pag. 78-78

Bîrcă Maria1, Rusnac Roman1, Birsanu Irina1, Balan Greta2, Petrenko Peter A.3, Gulya Aurelian3
 
1 Moldova State University,
2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
3 Institute of Applied Physics
 
 
Disponibil în IBN: 4 noiembrie 2019


Rezumat

N-Cyclohexyl-2-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(phenyl)methylene)hydrazinecarbothioamide (H2L) ligand was synthesized, according to the scheme:Characterization of novel 4-cyclohexylthiosemicarbazone was performed by FTIR-ATR spectroscopy, 1H-NMR and 13C-NMR.Two coordination compounds of copper(II) with this ligand were synthesized. Structure ofcoordination compounds were confirmed by IR spectroscopy, metal analysis and by single crystal X-ray diffraction:The compounds were also tested for antimicrobial activity:Coordination compounds were investigated for bacteriostatic and bactericideactivity on Staphylococcus aureus. The minimum inhibitory concentration for Staphylococcus aureus of [Cu(HL)Br]·C2H5OH and [Cu(HL)Cl]·C2H5OH is within 0.25 mg/mL, the minimum bactericide concentration is 0.5 mg/mL.