|Ultima descărcare din IBN:|
| SM ISO690:2012|
BACA, Svetlana; SULTANOVA, Olga; DARII, Mariana; BOUROSH, Pavlina. Inhibiting effect of hexammine-cobalt(III) trichloride bis(1,10-phenanthroline) on tumor growth in grapevine. In: Achievements and perspectives of modern chemistry. 9-11 octombrie 2019, Chişinău. Chisinau, Republic of Moldova: Tipografia Academiei de Ştiinţe a Moldovei, 2019, p. 72. ISBN 978-9975-62-428-2.
|Achievements and perspectives of modern chemistry 2019|
Conferința "International Conference "Achievements and perspectives of modern chemistry"" |
Chişinău, Moldova, 9-11 octombrie 2019
Bacterial cancer of the vine caused by oncogenic bacterium Rhizobium vitis is a harmful and widespread disease provoking the significant economic damage in viticulture industry. The lack of chemical substances against this grapevine disease has led to the fact that in the Republic of Moldova the disease still cannot be efficiently controlled and occurs in all areas of vine cultivation. In this regard, the development of new multicomponent compounds with antibacterial properties against oncogenic bacteria that cause the formation of tumors in plants is the most important challenge. Cobalt(III) coordination compounds showed remarkable biological activities and have found applications as antiviral and antibacterial agents . A new coordination compound with a formula [Co(NH3)6]Cl3.2(phen).3H2O (I) (Figure) has been prepared from the reaction of hexaminnecobalt(III) chloride with 1,10-phenanthroline. The 3D framework formed in 1 is stabilized by both electrostatic interactions between cations and anions, and strong intermolecular N–H...O, N–H...N, N–H...Cl and O–H...O hydrogen bonds. The cobalt(III) complex I has been tested for activity against Rhizobium (Agrobacterium)vitis and showed the significant antibacterial activity compared with commercial antibiotics andinhibited tumor growth.