To date an unprecedented, rapid change in environmental conditions is observed, which is likely to override the adaptive potential of plants, especially that of tree species with their long reproductive cycles. These environmental changes mainly originate from anthropogenic activities, which have caused air and soil pollution, acid precipitation, soil degradation, salinity, increasing UV-B radiation, climate change, etc. Some of these stress factors may fluctuate signifi-cantly in intensity and duration on time scales of hours, days, seasons, or years; others may change slowly and gradually affect plant growth conditions. The aim of this review was to investigate the physiological response of three species of trees Acer platanoides L; Populus nigra and Aesculus hippocastanum L. from five sites zones with different pollution. There were analysed the following indices: dry weight and total water quantity, chlorophylls, carotenes and total proteins amount that gradually were affected. The significant variations of chlorophylls concentration demonstrate that the photosynthetic system is highly sensible to pollution factors. In conclusion, according to our assays the studied species of trees are stress tolerant to pollutants and can be used as bioindicators.