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616.62-002-07-08 (1) |
Patologia sistemului urogenital. Boli urinare şi sexuale (genitale) (392) |
SM ISO690:2012 NABER, Kurt G.. New aspects for diagnostics and treatment of uncomplicated UTI. In: Arta Medica , 2019, nr. 1(70), p. 106. ISSN 1810-1852. |
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Arta Medica | ||||||
Numărul 1(70) / 2019 / ISSN 1810-1852 /ISSNe 1810-1879 | ||||||
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CZU: 616.62-002-07-08 | ||||||
Pag. 106-106 | ||||||
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Rezumat | ||||||
Acute uncomplicated cystitis (AC) in women is one of the most frequently diagnosed bacterial infection. A symptomatic urinary tract infection (UTI) must be differenciated from asymptomatic bacteriuria (ABU), which in general should not be treated and even may be protective sometimes. For therapy of AC old oral antibiotics (fosfomycin, nitrofurantoin, nitroxoline, pivmecillinam) should be prescribed. Fluoroquinolones, cephalosporines, and cotrimoxazole should only be used if first line antibiotics are not available or not suitable. With new therapeutic concepts not mainly elimination of bacteria but rather treatment of the inflammatory (over)reaction of the host is highlighted. Pilot studies with ibuprofen and with the phytodrug containing ingredients of centaury, lovage, and rosemary (Canephron®N) have demonstrated proof of this concept. To establish the significance of these therapeutic alternatives, results of phase 3 studies need to be awaited. If symptomatic therapy becomes more important, reliable clinical parameters are needed. The acute cystitis symptom score (ACSS) has now been validated in Uzbek, Russian and German languages; other languages will follow. Because of its high reliability, validity and predictive value the ACSS can be used not only in daily practice but also in clinical studies for diagnosis and outcome of AC in women. NOI |
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