Myasthenia Gravis (MG) is an autoimmune disorder, which affects acute or chronic neuromuscular junction. The disease is clinically manifested with muscular fatigability and motor weakness of affected segments, frequently delayed diagnosis explained by unpredictable evolution, like long term recoveries or myasthenic crisis with respiratory failure requiring assisted ventilation. It was performed a retrospective study on 28 cases of MG, to assess the clinical-evolutive aspects of the disease.