This research is a result of the study on the interdisciplinary correlation between medicine and biology in communication with professional guidance. The combination of the modern and traditional teaching and learning methodology of the Romanian language for the alofon students with professional orientation becomes a necessity in the context of the European Union's strategy and the global community. We propose an approach based on professional-oriented communication skills in terms of interdisciplinary correlation to ensure success in professional communication. The integrated curricular area is materialized in: special text lessons, new content assimilation lessons, workshop lessons, vocational communication skills evaluation lessons, assessment lessons. Integrating competence models with the common goal of correlating lexical units in medicine and biology will keep their interdisciplinary link and the didactic design of the curriculum will be based on the competency/sub-competency triad → content unit → teaching-learning activity.