Corelarea clinică între precondiţionarea ischemică cerebrală şi stupefierea ţesutului cerebral ischemiat
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GRUMEZA, Alexandru. Corelarea clinică între precondiţionarea ischemică cerebrală şi stupefierea ţesutului cerebral ischemiat . In: Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţe Medicale, 2008, nr. 5(19), pp. 90-92. ISSN 1857-0011.
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Buletinul Academiei de Ştiinţe a Moldovei. Ştiinţe Medicale
Numărul 5(19) / 2008 / ISSN 1857-0011

Corelarea clinică între precondiţionarea ischemică cerebrală şi stupefierea ţesutului cerebral ischemiat

Pag. 90-92

Grumeza Alexandru
 
 
Disponibil în IBN: 14 decembrie 2013


Rezumat

The study deals with stupefi ation fenomenon of cerebral tissue caused by internal carotid artery stenosis before and after endartectomy. Carotid endartherectomy was performed in the 15 patients with ischemic stroke, selected based on NASCET criteria, after expiration of conventional hours of therapeutic window. In this study were used following methods: neurological exam with sistematization of data according to Barthel index, investigations (cerebral CT and MRI), Doppler exam of carotid vessels, carotid angiography. The carotid endartherectomy initially being applied as method of secondary prevention of ischemic stroke, proved to be treatment option as well (signifi cant improvement of disability degree in ischemic stroke patients). The results of the study lead to the conclusion that ischemic cerebral tissue preserves the recuperation capacity after conventional hours of therapeutical window (stupefi ation fenomenon of ischemic cerebral tissue). This is the etiopatogenetic basis of the preconditioning fenomena of cerebral tissue largely described in the scientifi cal medical literature of the last period (animal models).