Health Information Systems (HIS) are the basis for planning, managing, and evaluating health care provision. However, many countries (both high‐ and low‐ income) face difficulties in introducing and adopting relevant eHealth applications in their clinical and technological environment. Health systems with limited resources are further challenged by the increasing demand for various electronic, especially facilitybased, HIS and the fact that technical assistance on-site is often missing. In the Republic of Moldova, a Swiss Program has introduced an Information- and Management System for Medical Devices used in the area of Perinatology and Paediatrics and could thereby rely on trained Biomedical Engineers for the implementation and maintenance of the IT tool since 2009. In the target setting, five out of nine secondary and the tertiary level healthcare providers currently employ Biomedical Engineers, whereas specialised IT experts are rare and only make-up for 17% of the technical staff working at the hospitals. To support the above mentioned tool and other HISs in smaller hospitals, Biomedical- or Clinical Engineers are often the only professionals present who act as interface between the technical and the medical world and provide valuable expertise. The adoption of various HIS applications at hospital level is thus an important task of Biomedical Engineers and this should be reflected in the professional education curriculum of the training institutions and in the job description of their employment.