<?xml version='1.0' encoding='utf-8'?>
<resource xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xmlns='http://datacite.org/schema/kernel-3' xsi:schemaLocation='http://datacite.org/schema/kernel-3 http://schema.datacite.org/meta/kernel-3/metadata.xsd'>
<identifier identifierType='DOI'>10.24110/0031-403X-2018-97-2-134-139</identifier>
<creators>
<creator>
<creatorName>Ababii, I.I.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Danilov, L.A.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Ginda  , S.S.</creatorName>
<affiliation>IMSP Institutul de Ftiziopneumologie „Chiril Draganiuc“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Maniuc, M.C.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Ababii, P.I.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Kostinov, M.P.</creatorName>
<affiliation>I. I. Mechnikov Research Institute for Vaccines and Sera, Rusia</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='en'>Clinical and immunological efficacy of conjugated pneumococcal vaccine in children with compensated chronic tonsillitis</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2018</publicationYear>
<relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>0031-403X</relatedIdentifier>
<subjects>
<subject>Cellular immunity</subject>
<subject>children</subject>
<subject>chronic tonsillitis</subject>
<subject>Conjugated pneumococcal vaccine</subject>
<subject>Markers of inflammation</subject>
</subjects>
<dates>
<date dateType='Issued'>2018-04-16</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Journal article</resourceType>
<descriptions>
<description xml:lang='en' descriptionType='Abstract'><p>The article presents results of conjugated pneumococcal vaccine use in combination with basic therapy in 64 children with chronic compensated tonsillitis. The study showed that vaccination assists activation of T-lymphocytes subpopulation, increases sensitization to bacterial antigens, normalization of proinflammatory cytokines content, which is clinically manifested in a significant decrease in acute respiratory infections incidences and antibacterial therapy courses for 2 years after vaccination compared to patients receiving a traditional therapy course.</p></description>
</descriptions>
<formats>
<format>uri</format>
</formats>
</resource>