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SM ISO690:2012 ROBU, Stephan V., FILIP, Vitalie, PRISAKARI, Viorel I., DIZDARI, Anna, GHEOACA, P., SPURCACI, B., CULEAC, Ion. Synthesis and characterization of copolymers based on styrene-butadiene grafted with antimicrobial agents. In: Nanotechnologies and Biomedical Engineering, Ed. 2, 18-20 aprilie 2013, Chișinău. Technical University of Moldova, 2013, Editia 2, pp. 405-408. ISBN 978-9975-62-343-8.. |
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Nanotechnologies and Biomedical Engineering Editia 2, 2013 |
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Conferința "International Conference on Nanotechnologies and Biomedical Engineering" 2, Chișinău, Moldova, 18-20 aprilie 2013 | |
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Pag. 405-408 | |
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The paper describes polymer materials based on styrene–butadiene grafted with antimicrobial components. The engraftment of copolymer styrene: butadiene-1,2 with methacrylic acid has been performed. The structure of grafted copolymer was confirmed by IR spectroscopy and by elemental analysis. It has been demonstrated that a rest of methacrylic acid joins the vinyl compound. Through an analogue polymer-transformation we succeeded in coupling of antimicrobial compounds such as ampicillin and others to ST:BD copolymer grafted with methacrylic acid. The structure of medicinal copolymer as well as the content of ampicillin has been confirmed by IR spectroscopy and elemental analysis. It has been shown that 65-70% COOH groups were subjected to transformation. Antimicrobial tests of medicinal copolymer demonstrated almost an identical activity of standard copolymer N-vinylpyrrolidone with metacrilic acid. The developed medicinal copolymer can be recommended for use in manufacturing of household items as well as of items of furniture, or part of the clinical household utensils having the possibility to improve the hygienic indices. |
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