Aminoalkylated carane-type aziridines were synthesized via epoxidation of (+)-3-carene by H ₂ O ₂ solution (7%) in EtOAc catalyzed by α-Al ₂ O ₃ nanoparticles, opening of the epoxide by NaN ₃ , and cyclization of the azidoalcohol by Ph ₃ P followed by condensation of the resulting aziridines with formalin and secondary amines. The cytotoxicity of the aminoalkylated aziridines with heteroorganic substituents increased on going from a five-membered pyrrolidine ring substituent to a six-membered piperidine ring and decreased sharply upon replacing a piperidine by a morpholine ring or increased on going to a piperazine ring. The structures of products were established using IR and NMR spectroscopy and an X-ray crystal structure analysis. .