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618.3-008.6:616.12-008.331.1 (2) |
Științe medicale. Medicină (11142) |
Patologia sistemului circulator, a vaselor sanguine. Tulburări cardiovasculare (975) |
SM ISO690:2012 CODREANU, Nadejda, BOTNARI-GUȚU, Mihaela, MURŞIEV, Cristina, CODREANU, Igor. Preeclampsia – riscuri precoce și tardive. In: Buletin de Perinatologie, 2019, nr. 1(82), pp. 22-29. ISSN 1810-5289. |
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Buletin de Perinatologie | ||||||
Numărul 1(82) / 2019 / ISSN 1810-5289 | ||||||
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CZU: 618.3-008.6:616.12-008.331.1 | ||||||
Pag. 22-29 | ||||||
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Despite edge research, at present preeclampsia remains a major proximity and an issue discussed in contemporary obstetrics. Preeclampsia is considered to be responsible for approximately 14% of maternal deaths estimated per year, constituting along with bleeding and infection a triad that may develop fatal complications during pregnancy. Th e purpose of this study is to present the impact of preeclampsia on the structure of maternal-fetal morbidity and mortality, long-term maternal risk. Th e risk of developing clinical hypertension by age 50 thus increases from 5% among women with healthy pregnancies to 20% in those with a history of severe preeclampsia. In women with severe preeclampsia, the odds of all associated CV complications – including ischemic heart disease (odds ratio [OR] 2.11; 1.76–2.52), stroke (OR 1.61; 1.35–1.93), thromboembolism (OR 2.18; 1.70–2.80), and type II diabetes (OR 4.09; 3.52–4.76)—are statistically higher. Th e result is an increase in death from all causes (OR 1.38; 1.11–1.71) in women at a mean follow-up age of 41.6 years. Material and Methods: Th e study was carried out in the Department of Obstetrics and Gynecology SCM -1 mun. Chisinau during 2010-2012 . Th e present study included 98 pregnant women whose pregnancy was complicated by preeclampsia of various degrees of severity, investigated according to the elaborated questionnaire. Study of obstetrical history of patients with a ischemic cardiovascular diseases. Th e study performed in the Cardiology department of IMSP SCM-3 mun. Chișinău during 2014-2016.. Th e study group included 52 patients. Results: Preeclampsia is a true proximity causing lethality between patients in the study in 4.1%, 21.4% – HELLP syndrome, 11.2% – embedded normal placental detachment and 7.1% – DIC with bleeding syndrome. Th e consequences of preeclampsia was pathological births, 81 cases completed by caesarean section or assisted births, of which they constitute 56.3% of premature births.Th e consequences of preeclampsia on fetuses showed an incidence of perinatal mortality by 4.3%, increased frequency of IUGR – 75.5% of cases, acute fetal distress – 37.8%. Th ere is a strong correlation between a history of preeclampsia and the risk of developing ischemic heart disease later in life. (p<0,001) Conclusion: Th is study showed that preeclampsia is associated with an increased risk for maternal and fetal morbidity. Th is study aims to highlight the value of life style modifi cations and to encourage clinicians to consider cardiovascular risk assessment and active management in women with a previous preeclampsia. |
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