| SM ISO690:2012|
GÎRBU, Vladilena; PRUTEANU, Elena; UNGUR, Nicon; BARBA, Alic; KULCIŢKI, Veaceslav. Terpene ozonolysis in green solvents. In: Ecological and environmental chemistry 2017The 6th International Conference. 2-3 martie 2017, Chișinău. Chisinau, Republic of Moldova: Academy of Sciences of Moldova, 2017, p. 229.
|Ecological and environmental chemistry 2017 2017|
Conferința "Ecological and environmental chemistry 2017" |
Chișinău, Moldova, 2-3 martie 2017
Nowadays, the chemical industry must develop cleaner chemical processes by the design of innovative and enviromentally benign chemical reactions. Green chemistry offers the tools to this approach, especially in chemistry of natural compounds. Terpenoids occur abundantly in natural sources. They show a remarcable diversity of structures and properties, therefore being atractive targets for direct industrial use as well as advanced chemical processing. A dramatic expansion of available terpenic building blocks can be acheived by ozonolitic cleavage of available representatives.1-3 We present in the current communication our first results on the use of dimethylcarbonate (DMC) and some deep eutectic mixtures (DES) as attractive eco-friendly ozonolysis solvents, which can diminish the negative impact of traditional volatile and toxic organic solvents currently used in ozonolitic transformations. Substrate of choice have been terpenes of different molecular weight and polarity, starting from unpolar monoterpenic hydrocarbons -pinene 1 and 3-carene 2 to moderately polar diterpenic sclareol 3. Aqueous H2O2 or other buffers have been used as cosolvents, which allowed elimination of separate reductive or oxidative steps. Reaction products 4-7 have been isolated chromatographically and properly identified (scheme below).