Nowadays, many research projects investigate the role of oxidative stress in the pathogenesis of different diseases, where free oxygen radicals act as signaling molecules in every phase of disease development. Therapeutic strategies which involve antioxidant substances are a potential option in redressing redox imbalances1. Considering the combined properties of the antioxidants radical scavengers and the thermic effect of the magnetite nanoparticles in alternative magnetic field, one interesting proposal is to engineer and to implement a magnetic complex-structured nano-entity able to intravascular deliver of anti-oxidant chemical species in a pharmacologically controlled and spatially guided manner, to simultaneous reduce ROS and to eradicate modified cells from cancer tumors by hyperthermia. To attempt this aim we intend to design, to prepare and to characterize a nano-size cargo-complex having a magnetic core and polyelectrolytes based shell (polyethyleneimine), loaded with precise amounts of natural organic radical scavengers. Since some natural antioxidants were reported to have antimicrobial properties, the antifungal and antimicrobial activities of the nanoparticles were measured using common pathogen agents met in care-associated diseases.