Sexual dysfunctions present a serious medical and social symptom that occurs in 10-52% of men and 25-63% of women. Organic causes of erectile dysfunction include hypogonadism, hyperprolactinaemia, and neurological disorders. Of the social causes of these disorders, the most important factor is stress. In addition, many treatments administered in case of diabetes mellitus, hypertension, and psychosis also contribute to worsening the situation with erectile dysfunction in men and libido in women. It is well known that people who suffer from stress and insomnia for a long time, their libido decreases, leading again to the onset of stress and insomnia, thus triggering a vicious circle of pathology. Currently available drugs and treatments intended for sexual dysfunctions, including erectile ones, are limited in effectiveness, are characterized by numerous unpleasant side effects and contra-indications in certain disorders. Sildenafil citrate (Viagra) is one of the most successful drugs for this purpose, which alters penile hemodynamic, causing common side effects such as headaches, facial flushing or redness, dyspepsia and nasal congestion. For these reasons, the development of effective new drugs with minimal adverse effects in the treatment of sexual dysfunction remains permanently the focus of researchers. Elaboration of preventive and therapeutic remedies based on natural aphrodisiacs is a perspective direction in the contemporary biomedicine. Starting from this, our researches have been focused on devising a remedy that, along with the antidepressant effect, also has aphrodisiac action. The selected form was a balm based on native vegetal raw material. It was elaborated a balm with aphrodisiac-like effect, containing macerate obtained by maceration of vegetable raw material in hydroalcoholic solution in a ratio of 1:3, respectively, in the following ratio of components, g: licorice root 1.5 - 2.5, sweet calamus rhizomes 0.10 - 0.16, aboveground parts of St. John’s wort 0.60 - 0.70, aerial parts of marjoram 0.49 - 0.55, peppermint leaves 0.78 - 0.84, aboveground parts of milfoil 0.70 - 0.80, pine buds 0.8 - 1.2, , acacia flowers 1.5 - 2.5, celery rhizomes with the aboveground part of celery 4.5 - 5.5, parsley root with the aboveground part of parsley 1.5 - 2.5. The balsam also contains hydroalcoholic extract of Spirulina platensis biomass of 20 mg/ml with a strength of 40 - 55% vol. 0.05 - 0.1 ml, hydroalcoholic extract of grape seeds of 0.05 mg/L with strength of 5 - 10% vol. 1.5 - 2.5 ml, alcoholic extract of walnut shells and septa of 10 mg/ml with strength of 45 - 55% vol. 0.05 - 0.1 ml, dessert red wine with strength of 16% vol. 300 - 400 ml, ethyl alcohol of 96% 285 - 289 ml and purified water up to 1000 ml. By developing this balm, we have expanded assortment of balms possessing high biological activity. The product priorities are the improvement of organoleptic properties due to the introduction of new ingredients and the significant increase in libido. This was also achieved due to selection of quantitative and qualitative ratio of balm components, their unique properties and synergistic effect manifested in mixing them. This balm was applied to 32 patients who displayed clinical signs of decrease in libido. Actually, 29 of them experienced obvious changes to increase testosterone levels in the blood, an average of 3.6 nmol/L, within 60 days towards data up to the use of balm. Thus, product peculiarities allow for an effective increase in the amount of testosterone and libido in people suffering from stress and insomnia, and the removal of the pathological vicious circle between stress and libido.