Antimicrobial activity of some copper (II) coordination compounds with N-(4-(2-((3-methyl-5-oxo-1-phenyl)-4,5-dihydro-1H-pyrazol)methylene) hidrazincarbotioamido)phenyl)acetamide
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2019-05-27 15:36
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BURDUNIUC, Olga; BALAN, Greta; RUSNAC, Roman; GULEA, Aurelian. Antimicrobial activity of some copper (II) coordination compounds with N-(4-(2-((3-methyl-5-oxo-1-phenyl)-4,5-dihydro-1H-pyrazol)methylene) hidrazincarbotioamido)phenyl)acetamide. In: Microbial Biotechnology. Ediția 4, 11-12 octombrie 2018, Chișinău. Chișinău, Republica Moldova: Institutul de Microbiologie şi Biotehnologie, 2018, p. 36. ISBN 978-9975-3178-8-7.
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Microbial Biotechnology
Ediția 4, 2018
Conferința "Microbial Biotechnology"
Chișinău, Moldova, 11-12 octombrie 2018

Antimicrobial activity of some copper (II) coordination compounds with N-(4-(2-((3-methyl-5-oxo-1-phenyl)-4,5-dihydro-1H-pyrazol)methylene) hidrazincarbotioamido)phenyl)acetamide


Pag. 36-36

Burduniuc Olga1, Balan Greta2, Rusnac Roman3, Gulea Aurelian3
 
1 National Agency for Public Health,
2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
3 State University of Moldova
 
Disponibil în IBN: 18 februarie 2019


Rezumat

Coordination compounds based on heterocyclic tiosemicarbazones are reported more frequently in the literature demonstrating a broad spectrum of antimicrobial, antifungal and anticancer properties. Coordination compounds of copper (II) are increasingly being investigated on different biological properties, the structural investigation of some copper (II) compounds was performed by infrared spectroscopy, 1H,13C-NMR spectroscopy and single crystal X-ray diffraction. This paper aims to elucidate the structure- antimicrobial activity relationship. The investigation of antimicrobial properties was performed on Staphylococcus aureus strains. Conclusion: The antimicrobial activity of studied copper (II) coordination compounds against Staphylococcus aureus was shown at minimal inhibitory concentrations of 0.0625– 0.2500 mg/mL.