New tandem synthesis of lignan structural analogs
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2019-01-22 16:19
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OBUSHAK, Mykola, HORAK, Yu., HOMZA, Yu., VAKHULA, A., MAKAEV, Fliur, LYTVYN, R.. New tandem synthesis of lignan structural analogs. In: The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova, 28-30 mai 2014, Chișinău. Chișinău, Republica Moldova: Institutul de Chimie al AȘM, 2014, p. 48.
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The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova 2014
Conferința "The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova"
Chișinău, Moldova, 28-30 mai 2014

New tandem synthesis of lignan structural analogs


Pag. 48-48

Obushak Mykola1, Horak Yu.1, Homza Yu.1, Vakhula A.1, Makaev Fliur2, Lytvyn R.1
 
1 Ivan Franko National University of Lviv,
2 Institute of Chemistry of the Academy of Sciences of Moldova
 
 
Disponibil în IBN: 21 ianuarie 2019


Rezumat

Tandem and domino reactions allow to obtain multinuclear compounds with relatively simple one pot procedure and fit well into the concept of green chemistry. We have developed new variations of tandem cyclizations based on sequential acylation/Diels-Alder reactions or Ugi/Diels-Alder reactions. This approach allows to synthesize partially hydrogenated isoindole, isobenzofuran derivatives and polycyclic fused systems by a single stage procedure. The newly synthesized compounds 410 are structural analogues of heterolignans 13.