Chemical composition and antimicrobial activity of the Levisticum officinale W.D.J. koch essential oil

Ciocarlan Alexandru; Dragalin Ion; Aricu Aculina; Lupaşcu Lucian; Ciocarlan Nina; Popescu Violeta

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2023-10-15 12:40

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581.135.51:582.92 (1)

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CIOCARLAN, Alexandru, DRAGALIN, Ion, ARICU, Aculina, LUPAŞCU, Lucian, CIOCARLAN, Nina, POPESCU, Violeta. Chemical composition and antimicrobial activity of the Levisticum officinale W.D.J. koch essential oil. In: Chemistry Journal of Moldova, 2018, nr. 2(13), pp. 63-68. ISSN 1857-1727. DOI: https://doi.org/10.19261/cjm.2018.514

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Chemistry Journal of Moldova

Numărul 2(13) / 2018 / ISSN 1857-1727 /ISSNe 2345-1688

Chemical composition and antimicrobial activity of the Levisticum officinale W.D.J. koch essential oil

DOI:https://doi.org/10.19261/cjm.2018.514

CZU: 581.135.51:582.92

Pag. 63-68

Ciocarlan Alexandru¹, Dragalin Ion¹, Aricu Aculina¹, Lupaşcu Lucian¹, Ciocarlan Nina², Popescu Violeta³

¹ Institute of Chemistry,
² National Botanical Garden (Institute) "Alexandru Ciubotaru",
³ Tiraspol State University

Disponibil în IBN: 24 decembrie 2018

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The chemical composition of industrially obtained Levisticum officinale W.D.J. Koch (lovage) essential oil of Moldovan origin was analysed by means of chromatographic (GC-MS) and spectral (IR, 1H and 13C NMR) methods. According to gas chromatography-mass spectrometry analysis of the studied essential oil, thirty-two known and two unknown constituents were identified. The main components of L. officinale essential oil are monoterpenic hydrocarbons, which make up to 53.50% of the total number of components. L. officinale essential oil is also characterized by a high content of oxygenated monoterpenes (alcohols, cetones and esters), which reaches up to 33.60%. For the first time the presence of 6-butyl-cyclohepta-1,4-diene (0.56%) and 7-formyl-4-methyl-cumarine (0.15%) in lovage essential oil is reported. Antibacterial and antifungal activities of mentioned oil were evaluated in vitro on five strains of microorganisms. It was found that lovage volatile oil (L. officinale) exhibits high antibacterial and antifungal properties in the range of concentrations 0.015-0.030%.

Cuvinte-cheie
Levisticum officinale, GC-MS analysis, antibacterial activity, antifungal activity., essential oil

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