In the offing the training process will focus on developing research competence based on the integration of acquired knowledge and skills. This interdisciplinary process requires the use of new teaching methods, which are based on the complex and multilateral study of substances and phenomen from nature, for the purpose of their conscious understanding. The proposed method is based on the determination of the probability (likelihood) of unfolding condensation process of organic molecules with the formation of new products. Also it is based on the integration of calculation for the determination of the energy of chemical systems and organic synthesis. The method is recommended for university education, also for pupils who are interested from pre-university education and optional.