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<identifier identifierType='DOI'>10.1002/cmdc.201800520</identifier>
<creators>
<creator>
<creatorName>Boldescu, V.V.</creatorName>
<affiliation>Institutul de Chimie al AŞM, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Sucman, N.S.</creatorName>
<affiliation>Institutul de Chimie al AŞM, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Hassan, S.</creatorName>
<affiliation>COMSATS Institute of Information Technology, Pakistan</affiliation>
</creator>
<creator>
<creatorName>Iqbal, J.</creatorName>
<affiliation>COMSATS Institute of Information Technology, Pakistan</affiliation>
</creator>
<creator>
<creatorName>Neamţu, M.</creatorName>
<affiliation>Universitatea "Alexandru Ioan Cuza", Iaşi, România</affiliation>
</creator>
<creator>
<creatorName>Lecka , J.</creatorName>
<affiliation>Université Laval, Québec, Canada</affiliation>
</creator>
<creator>
<creatorName>Sevigny, J.</creatorName>
<affiliation>Université Laval, Québec, Canada</affiliation>
</creator>
<creator>
<creatorName>Prodius, D.N.</creatorName>
<affiliation>Institutul de Chimie al AŞM, Moldova, Republica</affiliation>
</creator>
<creator>
<creatorName>Macaev, F.Z.</creatorName>
<affiliation>Institutul de Chimie al AŞM, Moldova, Republica</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='en'>Ectonucleotidase Inhibitory and Redox Activity of Imidazole-Based Organic Salts and Ionic Liquids</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2018</publicationYear>
<relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>1860-7179</relatedIdentifier>
<subjects>
<subject>antioxidants</subject>
<subject>cancer</subject>
<subject>ectonucleotidase</subject>
<subject>ionic liquids</subject>
<subject>organic salts</subject>
</subjects>
<dates>
<date dateType='Issued'>2018-11-06</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Journal article</resourceType>
<descriptions>
<description xml:lang='en' descriptionType='Abstract'><p>Cytotoxicity against cancer and normal cells, inhibition of ectonucleotidase, and redox properties of a new group of imidazole-based organic salts and ionic liquids were studied. The tetrachloroferrate salt of a 1-methylimidazole derivative of salicylic aldehyde had most prominent inhibitory activity against ectonucleotidase as well as a higher cytotoxicity against HeLa cells and lower cytotoxicity against BHK-21 cells than the reference compound carboplatin. The studied compounds exhibited a moderate level of antioxidant activity with better results for the salicylic aldehyde derivatives than for spiropyrans. Moreover, these compounds did not generate singlet oxygen.</p></description>
</descriptions>
<formats>
<format>uri</format>
</formats>
</resource>