Pharmacy in Moldova is undergoing a period of transition. The professional practice is adjusting to a market-oriented economy from the previous Soviet system. The pharmaceutical sector has been liberalised giving rise to a significant increase in the number of community pharmacies. This has led to some adverse effects on the profession of pharmacy with pharmacists having considerable difficulties fulfilling their professional aspirations and possibly losing confidence in further developing their professional role. Good pharmacy practice (GPP) is the heart of pharmacy profession; indeed it is the very essence of the profession. GPP is the practice of pharmacy that responds to the needs of the people who use the pharmacist?s services to provide optimal, evidence-based care. To support this practice it is essential that there be an established national frame work of quality standards and guidelines.