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Patologia sistemului circulator, a vaselor sanguine. Tulburări cardiovasculare (975) |
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SM ISO690:2012 SIDORENKO, Ludmila, DIAZ-RAMIREZ, Ivan, VOVC, Victor, BAUMANN, Gert. New approach to heart rate variability analysis based on cardiophysiological biomarkers. In: Moldovan Medical Journal, 2018, nr. 3(61), pp. 39-46. ISSN 2537-6373. DOI: https://doi.org/10.5281/zenodo.1465926 |
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Moldovan Medical Journal | ||||||
Numărul 3(61) / 2018 / ISSN 2537-6373 /ISSNe 2537-6381 | ||||||
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DOI:https://doi.org/10.5281/zenodo.1465926 | ||||||
CZU: UDC:616.12-008.313.2-073.97+612.172.2 | ||||||
Pag. 39-46 | ||||||
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Background: The heart rate variability (HRV) analysis is a well-known method demonstrating its value over the years in different medical fields. However, it still has its known limitations. Material and methods: The new approach to HRV analysis is based on a complementary HRV standard analysis with new cardiophysiological biomarkers. The biomarkers are assessed on cardiorhythmograms obtained by a 5-minute ECG recording using a specialized hardware (Polyspectrum-HRV-device, Neurosoft). Results: A possible applicative value of the biomarkers is shown on examples of how a prognosis for recurrence of atrial fibrillation (AFib) could be made. When in a rest-state cardiorhythmogram are observed LF drops and are followed by a pathological counterregulation, prognostically, recurrence of atrial fibrillation is expected. When in a cardiorhythmogram LF drops are observed and are followed by a physiological counterregulation, prognostically, sinus rhythm is expected. Physiological background of the biomarkers: increased central modulation of the heart in rest state of a patient, a sympathetic overflow of the heart in calm state and insufficiency of compensatory parasymphatetic counteractivation. Limitations of the paper: this is a methodological paper without description of patients. This paper will be followed by a clinical paper in which we are going to describe the validation of these cardiophysiological biomarkers on patients with AFib. Conclusions: Complementary to the standard HRV analysis, cardiophysiological biomarkers should be assessed: LF drops and HF counterregulation could be used for prognosis construction in cardiology. |
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Cuvinte-cheie cardiophysiological biomarkers, heart rate variability. |
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