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 SM ISO690:2012PORUBIN, Diana. Inhibition of in vitro nitrosation of nornicotine
. In: Chemistry Journal of Moldova, 2007, nr. 1(2), pp. 78-82. ISSN 1857-1727. |
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| Chemistry Journal of Moldova | ||||||
| Numărul 1(2) / 2007 / ISSN 1857-1727 /ISSNe 2345-1688 | ||||||
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| Pag. 78-82 | ||||||
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The inhibition of nornicotine nitrosation was studied. The concentration of nornicotine was 100 μM and nitrite 1000 μM. As inhibitors were used following compounds: ascorbic acid (as reference) (800, 1000, and 5000 μM), dihydroxyfumaric acid (1000 μM), ( )catechin (1000 μM), resveratrol (1000 μM), tartaric acid (1000 μM), quercetin (1000 μM), and grape seed extract (50, 100, 150 μg/ml). The best inhibitory effect was obtained for AAs
at 5000 μM (90.7%),( )Ct (95.5 %) and GSE at 150 μg/ml (96.1%). The small inhibitory effect was observed for TA – 22,5%.
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| Cuvinte-cheie N-nitrosonornicotine, nitrosation, inhibition, grape seed extract, polyphenol |
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