Since the early years of independence, Moldova has established relationships with several states. However, during the 90s, our country did not show a high interest for the major Western powers. The situation has evolved in the early 2000s, by increased cooperation with the European Union and the strengthening conviction that the Republic of Moldova is set towards an irreversible European path.  For this reason, the study aims to follow a historical intervention development of bilateral political, economic and cultural cooperation between Moldova and both external actors as partners and major political forces worldwide and in the region. In this respect, we will examine relations with the following countries: Germany, France, Italy, Great Britain and the United States, the countries being placed in alphabetical order.  Overall, we can identify the following steps in the foreign relations of the Republic of Moldova with the international community and the European Community:  1. 1992-1998 - period for setting diplomatic ties and signing of collaboration agreements;  2. 1998-2006 – period of relations strengthening and priorities identification, culminating in the signing of the Action Plan EU - Moldova  3. 2006 - present. The study will examine only the first and second stage, the third is reflected in another context.