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Căutarea după subiecte similare conform CZU |
616.3:616.5−002.525.2 (1) |
Patologia sistemului digestiv. Tulburări ale tubului alimentar (1732) |
Piele. Tegumente în general. Dermatologie clinică. Tulburări cutanate (210) |
SM ISO690:2012 MAZUR-NICORICI, Lucia. Caleidoscopul manifestărilor gastrointestinale în lupusul eritematos sistemic. In: Sănătate Publică, Economie şi Management în Medicină , 2017, nr. 4(74), pp. 43-49. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 4(74) / 2017 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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CZU: 616.3:616.5−002.525.2 | ||||||
Pag. 43-49 | ||||||
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Systemic lupus erythematosus (LES) is an inflammatory autoimmune systemic disease with various clinical manifestations, the gastrointestinal tract being one of the least frequent LES. However, most of the gastrointestinal manifestations are caused by drug-induced adverse reactions and infections, while disease-related symptoms are not as common as other organ diseases within lupus. The purpose of the research was to study the particularities of gastrointestinal manifestations in systemic lupus erythematosus. The history of the disease and the clinical and paraclinical examination were examined, in compliance with the criteria for classification of SLICC lupus, 2012, collected socio-demographic data, socio-economic status (SES), and specific researches for the detection of gastrointestinal pathology. We also estimated esophageal dysfunctions and dysfunctions that were associated with SS and high disease activity. Necrotizing gingivitis is a rare manifestation but associated with renal impairment and antiphospholipid syndrome with reserved prediction. Abdominal pain was found in pancreatitis, gastroduodenal ulcers and colitis, but also when no other nozology was diagnosed. Thus, pathologies such as ulcerative colitis, Crohn’s disease and collagen colitis were only detected in 2 cases, but it is noted that treatment with GCS or immunosuppressants often eclipses the clinical manifestations of these diseases. Concerning lupus mesenteric vasculitis, this pathology was diagnosed in 3 (2.3%) by surgery and 1 case of death. Note that gastrointestinal manifestations are commonly seen in lupus patients, but part is due to adverse drug reactions. Most gastrointestinal complications related to SLE are caused by vasculitis that responds well to corticosteroids and immunosuppressive agents. Early diagnosis and timely treatment are essential to improve prognosis. |
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Cuvinte-cheie systemic lupus erythematosus, digestive system, gastrointestinal system |
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