Research and Development services are the first of the services that support the process of innovation, innovation, and eco-innovation, with a special attention from developing countries that invest a significant percentage of GDP in these type of services. Studying the evolution of R & D services in the territorial profile is a major issue in the current context because these services are the first step in any stage of innovation, development, competitiveness, raising the standard of living of the population, increasing the economic well-being and social issues of a country. The purpose of this paper is to review the literature in the field and to analyze the evolution of the main relevant indicators in describing the level at which R & D services in Romania, and at the regional level, indicators for which there are publicly available statistical data in the official databases. The study, based on fundamental research in the field and the results of numerous bibliographic sources on this topic, uses specific statistical methods of territorial analysis. The obtained results outline an overview of the research and development services in Romania, but also at the level of the NUTS2 regions highlighting the gaps between them