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Articolul urmator |
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Ultima descărcare din IBN: 2023-12-11 14:30 |
SM ISO690:2012 AGOP, Silvia, CERNETCKII, O.. The Efficacy of Treatment with Valtrex of Genital Herpes in Pregnant Women
. In: Curierul Medical, 2011, nr. 4(322), pp. 3-5. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 4(322) / 2011 / ISSN 1875-0666 | ||||||
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Pag. 3-5 | ||||||
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Numerous publications are devoted to different aspects of genital herpes (GH) in pregnant women, to its negative influence over the development
of gestation period and the high incidence of perinatal mortality and morbidity. At the same time, the opinions over the administration of antiviral
treatment in pregnant women, is controversial. The study purpose: To evaluate the efficacy of treatment of GH infection with Valtrex in pregnant women.
Material and method: A retrospective study done during the years 2008-2009. he entire group of 70 pregnant women, included in the research, suffered
from GH during their pregnancy period. The group was divided into 2 groups, group I - which received antiviral treatment and group II - which did not
receive any antiviral treatment. Results and discussions: The pregnant women who have not received antiviral treatment, compared to the group I, had
a higher level of recurrent miscarriages, premature births, oligo- and polihidramnios, fetal growth retardation and placental insufficiency. In group II,
11.2% of early neonatal newborns died, the rate of neonatal morbidity reached up to 54.6%, compared to group I, where there were no neonatal deaths
and the perinatal morbidity rate is of 10.5%. The study, on children who were born by the mothers infected with genital herpes and who did not received
any treatment during pregnancy, has allowed us to determine 20.3% cases of neurological pathologies, compared with group I, where we had just 3.5%
cases. Conclusions: The high incidence of the recurrent miscarriages, perinatal mortality and morbidity, the neurologic sequelae in children who were
born by women who have had GH infection during their pregnancy and did not receive any etiological treatment, allow us to advise the administration
of Valtrex in antiviral treatment during pregnancy.
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Cuvinte-cheie genital herpes, pregnancy, Valtrex |
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