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SM ISO690:2012 BODRUG, Elena, GONCIAR, Veaceslav, LÎSÎI, Leonid. Antioxidant System in Experimental Toxic Hepatitis under the Influence of Enterosorption, Hyperbaric Oxygen Therapy and their Association. In: Curierul Medical, 2011, nr. 2(320), pp. 18-21. ISSN 1875-0666. |
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Curierul Medical | |||||
Numărul 2(320) / 2011 / ISSN 1875-0666 | |||||
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Pag. 18-21 | |||||
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The experiments carried out on 13 white rats focused on the study of the influence of enterosorption, hyperbaric oxygen therapy and their
association upon the intensity of the antioxidant system in the liver in acute toxic hepatitis induced by tetrachlormethane. Analysis of the results
revealed that acute toxic hepatitis leads to some insignificant disorders of the antioxidant system in the liver which manifest as a reduction in the
level of superoxide-dismutase (SOD), catalase, gamma-glutamyl transpeptidase and an increase in the amount of glutathione-reductase. The
medicinal charcoal and Medicas E enterosorbent contribute to restoration of the above mentioned disturbances, mainly when used for 14 days.
Enterosorption in association with hyperbaric oxygen therapy reduces the activity of gamma-glutamyl transpeptidase which is accompanied by
indirect changes of SOD, catalase and glutathione-reductase activity. |
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Cuvinte-cheie enterosorption, hyperbaric oxygen therapy, toxic hepatitis, antioxidant system |
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