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Ultima descărcare din IBN: 2022-10-05 16:28 |
SM ISO690:2012 TARAN, Natalia, LUPAŞCO, Iulianna, COJUHARI, M. Sindromul Peutz-Jeghers (Hipermelanocitozele epidermice sau Lentiginoza periorificială). In: Curierul Medical, 2011, nr. 1(319), pp. 66-70. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 1(319) / 2011 / ISSN 1875-0666 | ||||||
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Pag. 66-70 | ||||||
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Peutz-Jeghers syndrome (Epidermal Hipermelanocitosis or periorificial Lentiginosa)
Peutz-Jeghers syndrome (PJS) is a Hamartomatous Polyposis syndrome that is characterized by concomitant presence of gastrointestinal
polyposis and melanocytic maculele at the level of the lips, mouth and fingers. It is an autosomal dominant syndrome which appears with a ratio
of 1:200000 births. PJS clinical diagnosis can be suspected if two or more polyps of Peutz-Jeghers type are detected in the gastrointestinal tract or
if one Peutz-Jeghers polyp is associated with the characteristic pigmentation or with case history of heredocolaterale of PJS. We present a clinical
case which creates difficulties in diagnosis, being a rarely encountered nosology. The following disease requires surveillance and monitoring in
dynamics due to the increased risk of malignant: gastric, colo-rectal, lung, pancreatic, ovarian and breast cancer. |
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Cuvinte-cheie hyperpigmentation, gastric polyposis, Peutz Jeghers syndrome, hipermelanoze |
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