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SM ISO690:2012 CUCU, Tatiana, PÂNTEA, Victor, PLĂCINTĂ, Gheorghe, COJUHARI, Lilia, CEBOTARESCU, Valentin, CUCU, Cristina, MURAVCA, Tatiana. Tratamentul modern al hepatitei cronice virale B. In: Sănătate Publică, Economie şi Management în Medicină , 2014, nr. 4(55), pp. 59-64. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 4(55) / 2014 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 59-64 | ||||||
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The main treatment goal of the chronic hepatitis B is the permanent and profound suppression of the viral replication in order to prevent its complications, such as cirrhosis, liver failure and hepatocellular carcinoma. The ideal aim of the antiviral therapy is the disappearance of HBsAg, which can rarely be achieved with the currently available anti-HBV agents (interferons and nucleoside/nucleotide analogues). However, it has been shown that the majority of patients with chronic hepatitis B will present clinical improvement after the treatment with nucleoside/nucleotide oral drugs and the pharmacological class used will depend on the level of the viral load and on the clinical features of the patient. Another method of treatment that also presents interest is the therapeutic vaccination with the prophylactic vaccines with HBsAg, resulting in a temporary decrease of the viral load, which is more effective when used in combination with other antiviral treatments, and requiring further studies. |
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Cuvinte-cheie chronic viral hepatitis B, modern treatment, vaccination, suppression of the viral replication |
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