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Articolul precedent |
Articolul urmator |
658 5 |
Ultima descărcare din IBN: 2021-07-10 16:20 |
Căutarea după subiecte similare conform CZU |
616.155.392-07-085 (1) |
Patologia sistemului circulator, a vaselor sanguine. Tulburări cardiovasculare (975) |
SM ISO690:2012 MUSTEAŢĂ, Vasile. Opţiuni contemporane în diagnosticul şi managementul leucemiei mieloide cronice. In: Sănătate Publică, Economie şi Management în Medicină , 2016, nr. 2(66), pp. 195-200. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 2(66) / 2016 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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CZU: 616.155.392-07-085 | ||||||
Pag. 195-200 | ||||||
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Chronic myeloid leukemia (CML) is a clonal myeloproliferative tumor of hematopoietic system resulting from the stem cell malignant transformation, with maintenance of ability of differentiation of all cell lineages. The study enrolled 125 patients with different phases of CML who had been treated and followed up at the PMSI Institute of Oncology in 2004 – 2015. The prevalence of CML grows progressively: 2005– 2.11%ooo, 2010 – 3.40 %ооо, 2014 – 4.16%ooo. The patient age ranged from 19 to 81 years (median age – 46.1±2.13 years old), that indicated the predominant affection of the workable population. The discriminant analysis revealed the higher coefficients of canonical correlation (CC) for the following late diagnosis factors: an asymptomatic or oligosimptomatic onset of the disease (0.548), the insufficient level of the health literacy of population (0.525) and the onset with indiscrete clinical and paraneoplastic symptoms (0.340). 59.6±4.99% of patients were exposed to insolation during their daily activities (CC 0.479). The overall 3-year survival proved to be higher (p<0.05) in females (66%) than in males (51%). The median survival in the age group of 40–49 years (61.65±4.81 months) was superior (p<0.05) to that in the groups of 20–29 years (43.13±2.80 months) and over 70 years (43.14±3.92 months). The enrollment of CML patients in GIPAP and NOAT has considerably improved the short- and long-term results of treatment, contributing to their physical recovery, restoration of the ability to work and social reintegration. GIPAP and NOAT programs promote the improvement of the standards of diagnosis and treatment of CML in the Republic of Moldova |
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Cuvinte-cheie chronic myeloid leukemia, management, survival, prognosis factors, late diagnosis factors, physical recovery |
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