Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
584 4 |
Ultima descărcare din IBN: 2020-03-15 16:17 |
Căutarea după subiecte similare conform CZU |
616.36-002.12:578.891]-036.12-085 (1) |
Patologia sistemului digestiv. Tulburări ale tubului alimentar (1732) |
Virologie (442) |
SM ISO690:2012 LUPAŞCO, Iulianna, DUMBRAVA, Vlada-Tatiana. Tratamentul antiviral al pacienţilor cu hepatită cronică C (eficienţa și monitorizarea). In: Sănătate Publică, Economie şi Management în Medicină , 2016, nr. 4(68), pp. 69-73. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 4(68) / 2016 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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CZU: 616.36-002.12:578.891]-036.12-085 | ||||||
Pag. 69-73 | ||||||
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Rezumat | ||||||
Republic of Moldova is keeping a leader place in Europe in terms of the prevalence of chronic hepatitis C, early treatment of which can prevent progression ij liver cirrhosis. All of 54 HCV patients who received combination antiviral therapy with PEG IFN α2β + Ribavirin where closely followed up. Aviremia (negative ARN HCV) with sustained viral response (SVR) achieved in 70,83% of cases. Monitoring of clinical and biochemical parameters of patients with SVR showed diminishing values of ALT, AST, GGTP, but not to the normal values of the control group. In patients with a lack of ARN HCV and achieved SVR at 48-72 weeks of follow up were found abnormal indices of IgM, IgG, circulating immune complexes (CIC), indicating the persistence of immune disorders in chronic hepatitis HCV. During this period of observation of patients with chronic hepatitis HCV a thyroid dysfunction was found with an increase of thyroid stimulating hormone (TSH) level and titer of antibodies to thyroid peroxidase (anti-TPO). |
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Cuvinte-cheie chronic viral hepatitis C, treatment, PEG Interferon α2β |
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