As result of the theoretical and practical investigations of the 67 irrigation systems and sites, some important proposals were being necessary for the irrigation development in the Republic of Moldova in the actual conditions. It has been established that irrigation ensures an increase in the harvest of 30-80% on the gray soils, typical and levigated chernozems in the North and 180-250% on the ordinary and carbonate chernozems in the South (Andrieșet al., 1998; 2014). They regard at the equipment of the new irrigated lands at the area of 475 thou. hectares and reabilitation of lands equipped with the worst irrigation systems on the area of 125 thou. hectares. Principles are focused for an economic efficiency of the irrigated agricultural territories. The purpose of this paper is to analyze and generalize the situation on the field and determination of proposals to regulate basic principles of the development of irrigation in Republic of Moldova.