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SM ISO690:2012 MANCEVA, Maria, OPALCO, Igor, PĂDURE, Valeriu. Analiza comparativă a utilizării mifepristonului şi misoprostolului pentru
preinducţia naşterii premature cu retard de dezvoltare intrauterină a fătului
(RDIUF)
. In: Buletin de Perinatologie, 2014, nr. 3(63), pp. 14-20. ISSN 1810-5289. |
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Buletin de Perinatologie | |||||
Numărul 3(63) / 2014 / ISSN 1810-5289 | |||||
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Pag. 14-20 | |||||
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Rezumat | |||||
Objective: This study was undertaken to compare the efficacy of Mifepristone and Misoprostol for labor preinduction in women with the Intrauterine Growth Retardation Syndrome (IUGRS) at 22 – 36 6 weeks’ gestational age. Study design: 224 women with (IUGRS) were divided into 2 groups: I – 60 subjects were assigned to receive Mifepristone, II- 82 subjects received Misoprostol, while 82 women from the control group were in spontaneous labor. Results: the data of cervical ripening in the main treatment group was higher (the median Bishop score was 5,9±0,2) than in the other treatment group (the median Bishop score was 5,4±0,15) ,t= 2,23, р<0,05. Caesarean sections were performed in 5% of mifepristone-treated women, in 27,17% of misoprostol-treated subjects and in 4,88% of women in spontaneous labor (RR=0.98, 0.41 |
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