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SM ISO690:2012 TOFAN, Elena. Оптимизация фармакотерапии хронической сердечной недостаточности
. In: Curierul Medical, 2009, nr. 6(312), pp. 11-15. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 6(312) / 2009 / ISSN 1875-0666 | ||||||
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Pag. 11-15 | ||||||
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Optimization of Pharmacotherapy of Chronic Heart Insufficiency
The author examined the effects of different combinations of modern drugs on the clinical symptoms of chronic heart insufficiency (CHI)
and the consequent hemodynamics, morpho-functional heart parameters and the patients’ tolerance of physical effort. The study group consisted
of 80 patients with chronic heart insufficiency of the II-IV functional classes (FC) and an ejection fraction of the left ventricle (LV) of less than
45%. Through two-drug therapy the mean FC of the CHI decreased 12% after 48 weeks of continuous treatment and with three-drug therapy
in patients with CHI of III-IV FC the FC decreased by 20%. The combined therapy that included iATE or ARA-II and diuretics in patients with
CHI of II-III FC reduced the parameters of the LV and increased the ejection fraction (EF) by approximately 10%. Also, patients receiving the
tree-drug therapy decreased the parameters of the LV and increased the EF by approximately 18%.
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Cuvinte-cheie insuficienţă cardiacă cronică, modalităţi de tratament |
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