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Ultima descărcare din IBN: 2020-03-24 11:26 |
SM ISO690:2012 BUTOROV, Ivan, BUTOROV, Serghei, BODRUG, Nicolae, COJOCARU, Ala. Influenţa tratamentului de durată cu Prestarium asupra funcţiei sistolice şi celei diastolice ale ventriculului drept, la bolnavii cu bronhopneumopatie obstructivă cronică complicată cu cord pulmonar cronic
. In: Curierul Medical, 2009, nr. 4(310), pp. 18-22. ISSN 1875-0666. |
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Curierul Medical | ||||||
Numărul 4(310) / 2009 / ISSN 1875-0666 | ||||||
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Pag. 18-22 | ||||||
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Treatment with Prestarium in Patientes with Chronic Obstructive Pulmonary Disease and Chronic Pulmonary Heart
The results of the complex examination of 40 patients with chronic obstruction pulmonary diseases complicated with chronic pulmonary
heart showed up the activation of renin-angiotensin-aldosterone system (rising of renin and angiotensin converting enzyme activity, aldosterone
plasmatic concentration). The rising of renin activity and aldosterone concentration correlate with the level of pulmonary hypertension, hypoxemia,
structural and functional changes of right and left ventricle. The process of heart remodeling is characterized by increasing of anterior wall
thickness and dimensions of right ventricle and right auricle, signs of diastolic (impaired or pseudonormal relaxation) and systolic dysfunction
of right ventricle. The administration of inhibitor of angiotensin converting enzyme prestarium in compensated chronic pulmonary heart leads
to depression of average pressure in the pulmonary artery, improvement of right ventricle and left ventricle diastolic function, and a tendency to
decrease the thickness anterior wall of right ventricle, systolic and diastolic dimensions of both ventricles, dimensions of right auricle.
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Cuvinte-cheie chronic obstruction pulmonary diseases, chronic pulmonary heart, Prestarium |
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